Functional Bowel Disorders Program

Patient holding her stomach talking to a provider

Loyola Medicine offers one of the top programs in the Midwest for treating functional bowel diseases. These conditions, now called disorders of gut-brain interaction (DGBIs), cause ongoing digestive symptoms like pain, bloating, constipation, or diarrhea, even though there are no visible signs of disease in the digestive tract. They happen because the brain and gut aren't communicating properly, which can affect how the gut moves, feels, and reacts. Examples include irritable bowel syndrome (IBS), functional dyspepsia, and chronic nausea.

Why Loyola for Treatment of Digestive Disorders

Loyola’s multidisciplinary approach to gut-brain disorders ensures patients receive comprehensive care tailored to their specific symptoms and lifestyle. Our team includes board-certified gastroenterologists, clinical dietitians, health psychologists, physical therapists, and nurse practitioners who collaborate to diagnose and manage functional bowel disorders effectively.

Patients benefit from:

  • Advanced diagnostic tools to rule out other common gastrointestinal conditions
  • Integrated care that includes dietary support and brain-gut behavior therapy through Loyola's Gastrointestinal Behavior Medicine Program
  • Access to ongoing clinical research and the latest treatment options
  • A compassionate team focused on improving quality of life

Whether you’re dealing with ongoing bloating, unpredictable bowel habits, or upper abdominal discomfort, our team will work with you to create a plan that brings relief and control.

Meet Our Digestive Health Team  

Functional Bowel Disorders Providers  

Our team includes gastroenterologists, dietitians, and a psychologist trained in treating the mental and emotional aspects of digestive disorders. This team works together to create personalized care plans that treat both the body and mind, helping patients feel better and live more comfortably.   

Gastrointestinal Conditions Treated at Loyola Medicine

Functional bowel disorders are conditions characterized by chronic gastrointestinal symptoms without identifiable structural or biochemical abnormalities. These conditions arise from dysregulation between the central nervous system and the gastrointestinal tract, affecting motility, sensitivity, immune function, and microbiota.

The clinical specialists at Loyola are experts at diagnosing and managing patients with the following conditions:

  • Irritable bowel syndrome
  • Chronic constipation
  • Diarrhea
  • Fecal incontinence
  • Functional dyspepsia
  • Carbohydrate malabsorption/intolerance
  • Small intestinal bacterial overgrowth
  • Gastroparesis
  • Cyclic vomiting syndrome
  • Chronic nausea and vomiting
  • Chronic Intestinal Pseudo-obstruction
  • Pelvic Floor Dysfunction
  • Rectal Prolapse

Diagnostic Services Offered for Inflammatory Bowel Disease  

Many diagnostic studies are available to help evaluate and differentiate functional bowel disorders from other gastrointestinal conditions, such as inflammatory bowel disease. While functional disorders often present without structural abnormalities, these tests help rule out organic disease, assess motility, and evaluate subtle physiologic dysfunctions contributing to symptoms.  

Common GI Diagnostic Studies

Upper Endoscopy

Used to evaluate the esophagus, stomach, and upper part of the small intestine. It helps rule out inflammation, ulcers, or structural abnormalities in patients with upper GI symptoms such as nausea, vomiting, or early satiety.  

Colonoscopy

A procedure to examine the colon and rectum, often used to rule out structural or inflammatory causes of symptoms such as diarrhea, constipation, or rectal bleeding. Biopsies can help exclude microscopic colitis or other mucosal diseases.  

Anorectal Manometry

Assesses the function of the muscles and nerves in the rectum and anus. It is particularly useful in evaluating chronic constipation, fecal incontinence, and defecatory disorders.  

Breath Testing for Lactose and Fructose Malabsorption

Non-invasive tests that measure hydrogen and methane in the breath after ingestion of specific sugars. These tests can identify carbohydrate malabsorption, which can mimic or worsen functional GI symptoms.  

Breath Testing for Small Intestinal Bacterial Overgrowth

Measures hydrogen and methane production after ingestion of a sugar substrate (typically glucose or lactulose). Abnormal early gas production may indicate excessive bacteria in the small intestine, which can cause bloating, gas, and diarrhea.  

Gastric Emptying Studies

A nuclear medicine test that evaluates the rate at which the stomach empties food. Delayed gastric emptying (gastroparesis) or rapid transit may contribute to symptoms such as nausea, fullness, or bloating.  

Small Bowel Radiographic Series

A series of x-rays taken after ingesting contrast material to visualize the small intestine. Although less commonly used today, it may help detect subtle strictures or transit abnormalities in select cases.  

Cross-sectional Imaging (CT and MRI)

CT enterography or MR enterography provides detailed images of the bowel and surrounding structures. These modalities can help exclude inflammation, masses, or vascular abnormalities when functional symptoms raise concern for structural pathology.  

Defecography (MR or Fluoroscopic)

Provides imaging during simulated defecation to assess pelvic floor motion and structural abnormalities. Useful in patients with chronic constipation or suspected pelvic floor dysfunction.  

Treatments for Bowel Disorders

Effective treatment of functional bowel disorders begins with an accurate diagnosis. These disorders, encompassing conditions like irritable bowel syndrome (IBS), functional constipation, functional dyspepsia, and chronic nausea, are characterized by symptoms without structural or inflammatory disease, but often involve disturbances in motility, sensation, and brain-gut communication. A careful evaluation ensures appropriate therapy while avoiding unnecessary or invasive interventions.  

Dietary Changes  

Dietary modification is often the first step, especially in patients with identifiable food triggers or carbohydrate malabsorption. Elimination diets, such as low FODMAP, lactose-free, or fructose-restricted diets, can significantly improve symptoms in IBS and bloating. A registered dietitian experienced in gastrointestinal disorders is often instrumental in guiding patients through these plans to ensure nutritional adequacy and symptom relief.  

Medications  

For patients with constipation-predominant symptoms, first-line treatments often include over-the-counter fiber supplements, stool softeners, or osmotic laxatives. When symptoms persist despite these measures, prescription medications such as secretagogues or prokinetics may be used. In more complex or refractory cases, diagnostic tests such as anorectal manometry and balloon expulsion may identify pelvic floor dysfunction, which can be effectively treated with pelvic floor physical therapy and biofeedback training.  

Medical Therapies  

Medical therapies are frequently used to modulate gut motility and visceral sensitivity. These include antispasmodics, neuromodulators such as tricyclic antidepressants or SSRIs, and newer agents that target gut-specific neurotransmitters like serotonin. These treatments can help manage a range of symptoms including abdominal pain, bloating, chronic nausea, and altered bowel habits by restoring more normal function to the stomach and intestines.  

Behavioral Therapies

Behavioral therapy is a key part of our care for functional bowel disorders. At Loyola, we offer treatments like cognitive behavioral therapy (CBT), gut-directed hypnotherapy, and mindfulness-based stress reduction. These therapies are provided by a psychologist who is specially trained in gastrointestinal behavioral health. They help patients manage stress, reduce symptom flare-ups, and improve their quality of life. This holistic approach supports the brain-gut connection and complements medical and dietary treatments.  

Cognitive behavioral therapy, gut-directed hypnotherapy, and mindfulness-based approaches have been shown to be effective in reducing symptom severity and improving quality of life in both IBS and functional dyspepsia. These therapies help to recalibrate the brain-gut axis and are often offered in conjunction with medical or dietary treatment for optimal outcomes.  

Gut-Brain Interaction Research, Clinical Trials and Innovation

As an academic medical center, the Division of Gastroenterology and Nutrition places special emphasis on research. We view this as essential to advancing the field and improving outcomes for our patients. Loyola’s gastroenterology team has extensive experience in clinical care and clinical research. Advancements include being among the first to research:  

  • Overlap of IBS with IBD  
  • Role of behavioral therapies in the management of functional dyspepsia  
  • Medical management of dyspepsia  
  • Impact of sleep and stress on gastrointestinal symptoms  
  • Impact of IBS on quality of life  
  • Impact of gastroparesis in lung transplantation  
  • Role of nutrition support in gastroparesis  

Our program continues to maintain an active research presence with participation in clinical trials, treatment registries, as well as patient opportunities to be part of a research database focusing on the management of functional bowel disorders.

Learn more about our clinical trials.
Digestive Health

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From the most common digestive conditions to the more complex and rare gastrointestinal diseases, Loyola’s digestive health team will provide patients comprehensive care and treatments for hundreds of digestive conditions, disorders and diseases. Schedule an appointment today.

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