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Karen A Griffin, MD

Nephrology, Internal Medicine

Provider Groups

  • Loyola Medicine Physician

  • Loyola Physician Partners

Primary Contact

(888)584-7888
Appointments (New Patients Welcome)
Provider Groups
  • Loyola Medicine Physician

  • Loyola Physician Partners

Primary Contact
(888)584-7888

Services & Specialties

Areas of Specialization

  • Internal Medicine
  • Nephrology

Locations & Contact

Primary Location

Loyola University Medical Center

2160 S First Ave
Maywood , IL 60153

View hours
Tuesday
8:00am - 5:00pm
Monday
8:00am - 5:00pm
Wednesday
8:00am - 5:00pm
Thursday
8:00am - 5:00pm
Friday
8:00am - 5:00pm
Saturday
8:00am - 5:00pm
Sunday
8:00am - 5:00pm
Loyola University Medical Center

About

Dr. Griffin is a Professor of Medicine (Nephrology) at the Stritch School of Medicine, Loyola University and Renal Section Chief at the Edward Hines, Jr. V.A. Dr. Griffin received her medical degree from Rush University in Chicago, and subsequently completed her internal medicine residency and clinical/research fellowship in nephrology at Rush. As a clinician, she is primarily focused on hypertension and kidney disease and has been director of the Loyola University American Heart Association’s Designated Comprehensive Hypertension Center and has been recognized as a U.S. News and World Reports Top Doctor. Her research focus has been on the role of hypertension on the progression of chronic kidney disease and the impact of altered hemodynamics in the development and progression of diabetic and obesity-related nephropathies. She has received research funding from the NIH and Merit Review and published more than 80 articles, invited reviews and book chapters. Dr. Griffin has served as chair of the Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services of the Scientific Merit Review Board; the VA Merit Review Renal Study Section; and National Kidney Foundation of Illinois, Research committees. Additionally, she has served as a reviewer for several NIH study sections and been a member of several editorial boards and associate-editor of the ASN Nephrology Self-Assessment Program. She is currently Chair of the American Heart Association’s Council on Hypertension and Guest Editor of the journal Hypertension. She has served as a member of the American Society of Nephrology’s Hypertension Advisory Group. Dr. Griffin is a recipient of the American Medical Women's Association Awards for Leadership and Academic Excellence, The Student’s Choice Award at the Medical College of Wisconsin, the Arthur C. Corcoran Memorial Lecture of the American Heart Association Hypertension Council, and the Lois T. Ellison Lecture of the Medical College of Georgia.

Academic Title

Professor

Leadership Title

Medical Director, LUHS Comprehensive Hypertension Program
Fellowship Program Director, Nephrology

Ages Seen

Adults - Over 65
Adults - 18 to 64

Additional Resources

Education & Certifications

Education

Education:
Loyola University Chicago (1979)

Education:
Rush Medical College of Rush University (1983)

Board Certifications

Nephrology, Nephrology, American Board of Internal Medicine Subspecialty (1990)

Provider Groups

Loyola Medicine Physician

Loyola Physician Partners

Publications

  • Salt-Sensitive Hypertension and the Kidney. Nishimoto, M.; Griffin, K. A.; Wynne, B. M.; Fujita, T.; Hypertension (Dallas, Tex. : 1979)
  • Efficacy of Dynamics-based Features for Machine Learning Classification of Renal Hemodynamics. Chopde, P. R.; Álvarez-Cedrón, R.; Alphonse, S.; Polichnowski, A. J.; Griffin, K. A.; Williamson, G. A.; Proceedings of the ... European Signal Processing Conference (EUSIPCO). EUSIPCO (Conference)
  • Trends in Ambulatory Blood Pressure Monitoring in Five High-Volume Medical Centers. Juraschek, S. P.; Bello, N. A.; Chang, A. R.; Cluett, J. L.; Griffin, K. A.; Hinderliter, A.; Mukamal, K. J.; Ngo, L. H.; Turkson-Ocran, R. N.; Voora, R.; Vongpatanasin, W.; Hypertension (Dallas, Tex. : 1979)
  • Pathophysiology of unilateral ischemia-reperfusion injury: importance of renal counterbalance and implications for the AKI-CKD transition. Polichnowski, A. J.; Griffin, K. A.; Licea-Vargas, H.; Lan, R.; Picken, M. M.; Long, J.; Williamson, G. A.; Rosenberger, C.; Mathia, S.; Venkatachalam, M. A.; Bidani, A. K.; American journal of physiology. Renal physiology
  • Autoregulatory Efficiency Assessment in Kidneys Using Deep Learning. Alphonse, S.; Polichnowski, A. J.; Griffin, K. A.; Bidani, A. K.; Williamson, G. A.; Proceedings of the ... European Signal Processing Conference (EUSIPCO). EUSIPCO (Conference)
  • BP Fluctuations and the Real-Time Dynamics of Renal Blood Flow Responses in Conscious Rats. Bidani, A. K.; Polichnowski, A. J.; Licea-Vargas, H.; Long, J.; Kliethermes, S.; Williamson, G. A.; Griffin, K. A.; Journal of the American Society of Nephrology : JASN
  • KDOQI US Commentary on the 2017 ACC/AHA Hypertension Guideline. Kramer, H. J.; Townsend, R. R.; Griffin, K.; Flynn, J. T.; Weiner, D. E.; Rocco, M. V.; Choi, M. J.; Weir, M. R.; Chang, T. I.; Agarwal, R.; Beddhu, S.; American journal of kidney diseases : the official journal of the National Kidney Foundation
  • Celebrating 40 Years of Accomplishments. Dominiczak, A. F.; Kuo, D.; Bhalla, V.; Granger, J. P.; Griffin, K. A.; Hypertension (Dallas, Tex. : 1979)
  • Hypertensive Kidney Injury and the Progression of Chronic Kidney Disease. Griffin, K. A.; Hypertension (Dallas, Tex. : 1979)
  • Non-dialysis dependent chronic kidney disease is associated with high total and out-of-pocket healthcare expenditures. Small, C.; Kramer, H. J.; Griffin, K. A.; Vellanki, K.; Leehey, D. J.; Bansal, V. K.; Markossian, T. W.; BMC nephrology
  • Glomerulosclerosis in the diet-induced obesity model correlates with sensitivity to nitric oxide inhibition but not glomerular hyperfiltration or hypertrophy. Polichnowski, A. J.; Licea-Vargas, H.; Picken, M.; Long, J.; Bisla, R.; Williamson, G. A.; Bidani, A. K.; Griffin, K. A.; American journal of physiology. Renal physiology
  • Hemodynamic basis for the limited renal injury in rats with angiotensin II-induced hypertension. Polichnowski, A. J.; Griffin, K. A.; Picken, M. M.; Licea-Vargas, H.; Long, J.; Williamson, G. A.; Bidani, A. K.; American journal of physiology. Renal physiology
  • Critical blood pressure threshold dependence of hypertensive injury and repair in a malignant nephrosclerosis model. Griffin, K. A.; Polichnowski, A.; Litbarg, N.; Picken, M.; Venkatachalam, M. A.; Bidani, A. K.; Hypertension (Dallas, Tex. : 1979)
  • Severe renal mass reduction impairs recovery and promotes fibrosis after AKI. Polichnowski, A. J.; Lan, R.; Geng, H.; Griffin, K. A.; Venkatachalam, M. A.; Bidani, A. K.; Journal of the American Society of Nephrology : JASN
  • Blood pressure-renal blood flow relationships in conscious angiotensin II- and phenylephrine-infused rats. Polichnowski, A. J.; Griffin, K. A.; Long, J.; Williamson, G. A.; Bidani, A. K.; American journal of physiology. Renal physiology
  • Renal microvascular dysfunction, hypertension and CKD progression. Bidani, A. K.; Polichnowski, A. J.; Loutzenhiser, R.; Griffin, K. A.; Current opinion in nephrology and hypertension
  • Hypertension and chronic kidney disease progression: why the suboptimal outcomes? Bidani, A. K.; Griffin, K. A.; Epstein, M.; The American journal of medicine
  • Large BP-dependent and -independent differences in susceptibility to nephropathy after nitric oxide inhibition in Sprague-Dawley rats from two major suppliers. Griffin, K.; Polichnowski, A.; Licea-Vargas, H.; Picken, M.; Long, J.; Williamson, G.; Bidani, A.; American journal of physiology. Renal physiology
  • Protective importance of the myogenic response in the renal circulation. Bidani, A. K.; Griffin, K. A.; Williamson, G.; Wang, X.; Loutzenhiser, R.; Hypertension (Dallas, Tex. : 1979)
  • Angiotensin II type 2 receptor in chronic kidney disease: the good side of angiotensin II? Griffin, K. A.; Bidani, A. K.; Kidney international
  • Potential risks of calcium channel blockers in chronic kidney disease. Griffin, K. A.; Bidani, A. K.; Current cardiology reports
  • Adverse renal consequences of obesity. Griffin, K. A.; Kramer, H.; Bidani, A. K.; American journal of physiology. Renal physiology
  • Dynamic blood pressure load and nephropathy in the ZSF1 (fa/fa cp) model of type 2 diabetes. Griffin, K. A.; Abu-Naser, M.; Abu-Amarah, I.; Picken, M.; Williamson, G. A.; Bidani, A. K.; American journal of physiology. Renal physiology
  • Progression of renal disease: renoprotective specificity of renin-angiotensin system blockade. Griffin, K. A.; Bidani, A. K.; Clinical journal of the American Society of Nephrology : CJASN
  • The benefits of renin-angiotensin blockade in hypertension are dependent on blood-pressure lowering. Bidani, A. K.; Griffin, K. A.; Nature clinical practice. Nephrology
  • Spontaneously reduced blood pressure load in the rat streptozotocin-induced diabetes model: potential pathogenetic relevance. Bidani, A. K.; Picken, M.; Hacioglu, R.; Williamson, G.; Griffin, K. A.; American journal of physiology. Renal physiology
  • Hypertension and kidney damage. Griffin, K. A.; Journal of clinical hypertension (Greenwich, Conn.)
  • Differential effects of salt on renal hemodynamics and potential pressure transmission in stroke-prone and stroke-resistant spontaneously hypertensive rats. Abu-Amarah, I.; Bidani, A. K.; Hacioglu, R.; Williamson, G. A.; Griffin, K. A.; American journal of physiology. Renal physiology
  • Pathophysiology of hypertensive renal damage: implications for therapy. Bidani, A. K.; Griffin, K. A.; Hypertension (Dallas, Tex. : 1979)
  • Hypertensive renal damage: insights from animal models and clinical relevance. Griffin, K. A.; Bidani, A. K.; Current hypertension reports
  • Effects of calcium channel blockers on "dynamic" and "steady-state step" renal autoregulation. Griffin, K. A.; Hacioglu, R.; Abu-Amarah, I.; Loutzenhiser, R.; Williamson, G. A.; Bidani, A. K.; American journal of physiology. Renal physiology
  • Blood pressure lability and glomerulosclerosis after normotensive 5/6 renal mass reduction in the rat. Griffin, K. A.; Picken, M. M.; Bidani, A. K.; Kidney international
  • Long-term blood-pressure monitoring in unrestrained animals. Griffin, K. A.; Abu-Amarah, I.; Bidani, A. K.; Methods in molecular medicine
  • "Step" vs. "dynamic" autoregulation: implications for susceptibility to hypertensive injury. Bidani, A. K.; Hacioglu, R.; Abu-Amarah, I.; Williamson, G. A.; Loutzenhiser, R.; Griffin, K. A.; American journal of physiology. Renal physiology
  • Low protein diet mediated renoprotection in remnant kidneys: Renal autoregulatory versus hypertrophic mechanisms. Griffin, K. A.; Picken, M.; Giobbie-Hurder, A.; Bidani, A. K.; Kidney international
  • Renoprotection by ACE inhibition or aldosterone blockade is blood pressure-dependent. Griffin, K. A.; Abu-Amarah, I.; Picken, M.; Bidani, A. K.; Hypertension (Dallas, Tex. : 1979)
  • Long-term renal consequences of hypertension for normal and diseased kidneys. Bidani, A. K.; Griffin, K. A.; Current opinion in nephrology and hypertension
  • Genetic susceptibility to renal injury in hypertension. Bidani, A. K.; Griffin, K. A.; Churchill, P. C.; Churchill, M. C.; St Lezin, E.; Kurtz, T. W.; Experimental nephrology
  • Comparative effects of selective T- and L-type calcium channel blockers in the remnant kidney model. Griffin, K. A.; Picken, M.; Bakris, G. L.; Bidani, A. K.; Hypertension (Dallas, Tex. : 1979)
  • Differential salt-sensitivity in the pathogenesis of renal damage in SHR and stroke prone SHR. Griffin, K. A.; Churchill, P. C.; Picken, M.; Webb, R. C.; Kurtz, T. W.; Bidani, A. K.; American journal of hypertension
  • Relative antihypertensive and glomeruloprotective efficacies of enalapril and candesartan cilexetil in the remnant kidney model. Griffin, K. A.; Picken, M. M.; Bakris, G.; Bidani, A. K.; Journal of the renin-angiotensin-aldosterone system : JRAAS
  • Calcium-channel blockers and the progression of renal disease. Griffin, K. A.; Bidani, A. K.; Current hypertension reports
  • Lack of evidence of blood pressure-independent protection by renin-angiotensin system blockade after renal ablation. Bidani, A. K.; Griffin, K. A.; Bakris, G.; Picken, M. M.; Kidney international
  • Functional and structural correlates of glomerulosclerosis after renal mass reduction in the rat. Griffin, K. A.; Picken, M. M.; Churchill, M.; Churchill, P.; Bidani, A. K.; Journal of the American Society of Nephrology : JASN
  • Class differences in the effects of calcium channel blockers in the rat remnant kidney model. Griffin, K. A.; Picken, M. M.; Bakris, G. L.; Bidani, A. K.; Kidney international
  • Deleterious effects of calcium channel blockade on pressure transmission and glomerular injury in rat remnant kidneys. Griffin, K. A.; Picken, M. M.; Bidani, A. K.; The Journal of clinical investigation
  • Radiotelemetric BP monitoring, antihypertensives and glomeruloprotection in remnant kidney model. Griffin, K. A.; Picken, M.; Bidani, A. K.; Kidney international
  • Renal ablation acutely transforms 'benign' hypertension to 'malignant' nephrosclerosis in hypertensive rats. Bidani, A. K.; Griffin, K. A.; Plott, W.; Schwartz, M. M.; Hypertension (Dallas, Tex. : 1979)
  • Method of renal mass reduction is a critical modulator of subsequent hypertension and glomerular injury. Griffin, K. A.; Picken, M.; Bidani, A. K.; Journal of the American Society of Nephrology : JASN
  • Genetic predisposition to hypertension and microvascular injury in the remnant kidney model. Bidani, A. K.; Griffin, K. A.; Plott, W.; Schwartz, M. M.; The Journal of laboratory and clinical medicine
  • Continuous telemetric blood pressure monitoring and glomerular injury in the rat remnant kidney model. Bidani, A. K.; Griffin, K. A.; Picken, M.; Lansky, D. M.; The American journal of physiology
  • Role of endothelium-derived nitric oxide in hemodynamic adaptations after graded renal mass reduction. Griffin, K. A.; Bidani, A. K.; Ouyang, J.; Ellis, V.; Churchill, M.; Churchill, P. C.; The American journal of physiology
  • Prostaglandins do not mediate impaired autoregulation or increased renin secretion in remnant rat kidneys. Griffin, K. A.; Bidani, A. K.; Picken, M.; Ellis, V. R.; Churchill, P. C.; The American journal of physiology
  • The technique of percutaneous renal biopsy. How to minimize risk while ensuring adequate tissue sampling. Griffin, K. A.; The Journal of critical illness