Studies Presented at Poster Session | News | Loyola Medicine
Monday, June 15, 2015

Oncology, infectious disease and immunology studies presented at Loyola poster session

49 studies highlight strong science conducted at Loyola

MAYWOOD, Ill. (June 15, 2015) – Forty-nine scientific studies were presented during a research night sponsored by the Oncology Research Institute and Infectious Disease and Immunology Research Institute of Loyola University Chicago Stritch School of Medicine.

Two researchers from each research institute were awarded prizes for the best poster presentations.

Winning posters from the Oncology Research Institute are:

 

  • “COMPASS-like coactivator complex regulation of the bantam miRNA enhancer,” by David Ford, a PhD student in the lab of  Andrew Dingwall, PhD. "The genes we study recently have been discovered to be among the most frequently mutated genes in a large variety of cancers, including breast, uterine, bladder, stomach, lung, melanoma, lymphoma, and some leukemias,” Mr. Ford explained. “These critically important genes function to guide proper development and cell metabolism. Our research findings, using a combination of genetic, molecular and biochemical techniques, will provide insights into the roles of these genes in healthy cells and tumors, and aid in the generation of novel therapeutics." 
  • “Receptor targeting in drug-resistant breast cancer,” by Andrew Baker, a PhD student in the lab of Clodia Osipo, PhD.  “Our work focuses on targeting receptors that allow breast cancer cells to become resistant to first-line therapies,” Mr. Baker explained. “These receptors enable breast cancer cells to become increasingly aggressive in tumor formation and metastasis.”

Winning posters from the Infectious Disease and Immunology Research Institute are:

  • “A novel role for umbilical cord blood monocytes in inducing CD4 and CD8 regulatory T Cells,” by Jessica Lee, a MD/PhD student in the lab of Makio Iwashima, PhD. “We examined why newborns have a weak immune system, and found a group of cells that prevent immune responses,” Ms. Lee explained. “Understanding how these cells work may help develop better vaccines for infants and may improve therapies for unwanted immune responses such as autoimmune diseases.” 
  • “Mechanisms by which commensal exopolysaccharides limit inflammation,” by Mallory Paynich, a PhD student in the lab of Katherine Knight, PhD.  “We have identified a probiotic molecule that might be used to prevent traveler’s diarrhea and other forms of colitis, including ulcerative colitis, Crohn’s disease, and celiac disease,” Ms. Paynich explained. “We now are designing similar therapeutics for the treatment and prevention of other human diseases.”

The work of the four winners, like that of other researchers who presented posters, “highlights the strong science being conducted at Loyola,” said Michael I. Nishimura, PhD, who co-directs the Oncology Research Institute along with Patrick Stiff, MD.

The Infectious Disease and Immunology Research Institute is directed by James Cook, MD, and Adam Driks, PhD.

The mission of the Oncology Research Institute is to support research in the mechanisms of cancer. The mission of the Infectious Disease and Immunology Research Institute is to understand interactions between microbes and the immune system, and to translate this knowledge to the treatment, control and prevention of diseases caused by human infectious agents.

About Loyola Medicine and Trinity Health

Loyola Medicine, a member of Trinity Health, is a quaternary care system based in the western suburbs of Chicago that includes Loyola University Medical Center (LUMC), Gottlieb Memorial Hospital, MacNeal Hospital and convenient locations offering primary and specialty care services from 1,877 physicians throughout Cook, Will and DuPage counties. LUMC is a 547-licensed-bed hospital in Maywood that includes the William G. and Mary A. Ryan Center for Heart & Vascular Medicine, the Cardinal Bernardin Cancer Center, a Level 1 trauma center, Illinois's largest burn center, a certified comprehensive stroke center and a children’s hospital. Having delivered compassionate care for over 50 years, Loyola also trains the next generation of caregivers through its teaching affiliation with Loyola University Chicago’s Stritch School of Medicine and Marcella Niehoff School of Nursing. Gottlieb is a 247-licensed-bed community hospital in Melrose Park with 150 physician offices, an adult day care program, the Gottlieb Center for Fitness, the Loyola Center for Metabolic Surgery and Bariatric Care and the Loyola Cancer Care & Research at the Marjorie G. Weinberg Cancer Center at Melrose Park. MacNeal Hospital is a 374-bed teaching hospital in Berwyn with advanced inpatient and outpatient medical, surgical and psychiatric services, advanced diagnostics and treatments. MacNeal has a 12-bed acute rehabilitation unit, a 25-bed inpatient skilled nursing facility, and a 68-bed behavioral health program and community clinics. MacNeal has provided quality, patient-centered care to the near west suburbs since 1919.

Trinity Health is one of the largest multi-institutional Catholic healthcare systems in the nation, serving diverse communities that include more than 30 million people across 22 states. Trinity Health includes 92 hospitals, as well as 109 continuing care locations that include PACE programs, senior living facilities and home care and hospice services. Its continuing care programs provide nearly 2.5 million visits annually. Based in Livonia, Mich., and with annual operating revenues of $18.3 billion and assets of $26.2 billion, the organization returns $1.1 billion to its communities annually in the form of charity care and other community benefit programs. Trinity employs about 129,000 colleagues, including 7,800 employed physicians and clinicians. Committed to those who are poor and underserved in its communities, Trinity is known for its focus on the country's aging population. As a single, unified ministry, the organization is the innovator of Senior Emergency Departments, the largest not-for-profit provider of home health care services—ranked by number of visits—in the nation, as well as the nation’s leading provider of PACE (Program of All Inclusive Care for the Elderly) based on the number of available programs.