Thursday, April 24, 2008

Loyola Transplant Surgeon Pioneers New Way to Increase Supply of Organs

Palatine Patient Says Lung Transplant

MAYWOOD, Ill. - Transplant surgeons such as Dr. Robert Love of Loyola University Health System are pioneering a new way to increase the supply of organs from deceased donors.

Today, most organs are obtained from donors on life support who have been declared brain dead. The organs are in good condition because the heart is still beating.

But more surgeons are beginning to use organs from patients who have been declared dead after their hearts have stopped beating. Last year, there were 793 donations after cardiac death in the United States. That's up from 117 cases in 2000.

Kidneys and livers are the most commonly used organs from cardiac-death donors, but surgeons also are using lungs and pancreases. Love has done about 30 lung transplants from cardiac-death donors.

Nearly 100,000 people are waiting for organ transplants in the U.S. Some people wait for years. And many die while still on the list.

"We must do everything we can to encourage people to become organ donors," Love said. "And we also have to make sure that every usable organ is used." Love is a professor of thoracic and cardiovascular surgery at Loyola University Chicago Stritch School of Medicine.

Steve Schumann of Palatine is among the patients of Love who have benefited from a cardiac-death donation. The 60-year-old pharmacist had pulmonary fibrosis, a progressive and incurable lung disease. Schumann had uncontrollable coughing fits, and needed oxygen 24 hours a day, even in the shower.

Without a lung transplant, Schumann did not have long to live. If his only option had been a transplant from a brain-dead donor, an organ might not have become available soon enough to save his life, Love said. Fortunately, Schumann's time on the waiting list was shortened when a pair of lungs became available from a cardiac-death donor.

Last July, Love and Loyola surgeon Dr. Michael Eng traveled to the donor's hospital in Joliet to recover the lungs. Love brought the organs back to Loyola in an ambulance, and performed the transplant along with Dr. Mamdouh Bakhos.

Shortly after waking up from surgery, Schumann's new lungs filled with air. For the first time in more than two years, he could breathe without an oxygen tank.

"The feeling was indescribable," Schumann said. "It was such a relief."

Schumann can walk again, without gasping for breath or being tethered to an oxygen tank. He has just joined an over-fifty softball league, and plans to play as much golf as possible this summer.

"It was a miracle," he said.

Obtaining organs from cardiac-death donors can be technically challenging. Organs begin to deteriorate as soon as the heart stops beating. Surgeons generally have only a 30-minute to 60-minute window to remove organs.

A typical case involves a patient who has suffered severe and irreversible brain damage from, for example, a car accident, gunshot wound or brain hemorrhage. The patient still has minimal brain function so is not considered brain dead. But the patient is near death, and further treatment is considered futile. The family agrees to withdraw the patient from life support and donate the organs.

The patient usually dies shortly after being taken off the ventilator and other life support, such as medications to maintain blood pressure. Five minutes after the patient's heart stops beating, the body is taken to an operating room, where the organs are recovered.

Donation after cardiac death leaves the family little time to say goodbye. "But families are usually very understanding about this," said Joyce Maly, Loyola's in-house coordinator for organ and tissue donation. Maly's position is a partnership between Loyola and Gift of Hope Organ and Tissue Donor Network.

Families take solace from knowing that their loved-ones' organs will enable other people to live. "They are living on in someone else," Maly said.


Loyola University Health System, a wholly owned subsidiary of Loyola University Chicago (LUC), includes the private teaching hospital at Loyola University Medical Center (LUMC), 22 specialty and primary care centers in the western and southwestern suburbs, the Loyola Ambulatory Surgery Center at Oakbrook and the Loyola Oakbrook Terrace Imaging Center; and serves as co-owner-operator of RML Specialty Hospital, a long-term acute hospital specializing in ventilation weaning and other medically complex patients in suburban Hinsdale, Ill. Loyola is nationally recognized for its specialty care and groundbreaking research in cancer, neurological disorders, neonatology and the treatment of heart disease. The 61-acre medical center campus in Maywood, Ill., includes the 570-licensed bed Loyola University Hospital with a Level I trauma center, the region's largest burn unit, one of the Midwest's most comprehensive organ transplant programs, the Russo Surgical Pavilion and the Ronald McDonald® Children's Hospital of LUMC. Also on campus are Loyola's Center for Heart & Vascular Medicine, the Cardinal Bernardin Cancer Center, Loyola Outpatient Center and LUC Stritch School of Medicine. The medical school includes the Cardiovascular Institute, Oncology Institute, Burn & Shock Trauma Institute, Neuroscience Institute and the Neiswanger Institute for Bioethics and Health Policy.

About Loyola University Health System

Loyola University Health System (LUHS) is part of Trinity Health. Based in the western suburbs of Chicago, LUHS is a quaternary care system with a 61-acre main medical center campus, the 36-acre Gottlieb Memorial Hospital campus and more than 30 primary and specialty care facilities in Cook, Will and DuPage counties. Loyola University Medical Center’s campus is conveniently located in Maywood, 13 miles west of Chicago’s Loop and 8 miles east of Oak Brook, Ill. At the heart of the medical center campus is a 559-licensed-bed hospital that houses a Level 1 Trauma Center, a Burn Center and the Ronald McDonald® Children's Hospital of Loyola University Medical Center. Also on campus are the Cardinal Bernardin Cancer Center, Loyola Outpatient Center, Center for Heart & Vascular Medicine and Loyola Oral Health Center as well as Loyola University Chicago Stritch School of Medicine, Loyola University Chicago Marcella Niehoff School of Nursing and the Loyola Center for Fitness. Loyola's Gottlieb campus in Melrose Park includes the 255-licensed-bed community hospital, the Professional Office Building housing 150 private practice clinics, the Adult Day Care, the Gottlieb Center for Fitness, Loyola Center for Metabolic Surgery and Bariatric Care and the Loyola Cancer Care & Research at the Marjorie G. Weinberg Cancer Center at Melrose Park.

Trinity Health is a national Catholic health system with an enduring legacy and a steadfast mission to be a transforming and healing presence within the communities we serve. Trinity is committed to being a people-centered health care system that enables better health, better care and lower costs. Trinity Health has 88 hospitals and hundreds of continuing care facilities, home care agencies and outpatient centers in 21 states and 119,000 employees.