MAYWOOD, Ill. -- A review article about the immune system and aging, written by Loyola University Health System researcher Elizabeth J. Kovacs, PhD, and colleagues, has been named one of the Top 10 most-cited articles in the journal Experimental Gerontology for the period 2008-2010. The article, published in the August 2008 issue, is titled "Innate Immunity and Aging." Kovacs is senior author. The article describes how advanced age is associated with defects in all cells of the innate immune system. A dysfunctional immune system is a contributing factor to poor outcomes after injuries and infections, and to many diseases common in the elderly. "Gaining an understanding of the nature of the defects in innate immune cells may allow the development of therapeutic strategies aimed to restore innate immune function in aged individuals," Kovacs and colleagues wrote. Kovacs is director of research in the Burn & Shock Trauma Institute, a professor in the Departments of Surgery and Microbiology & Immunology, and a member of the Immunology & Aging Program at Loyola University Chicago Stritch School of Medicine. Co-authors are first author Christian Gomez, PhD, a former postdoctoral fellow in Kovacs' lab who now is at the Mayo Clinic; Douglas E. Faunce, PhD, now a senior principal scientist at Pfizer, Inc.; and Vanessa Nomellini, MD, PhD, now a general surgery resident at the University of Wisconsin Hospital.
Loyola Researcher's Article among Top 10 Most Cited in Experimental Gerontology Journal
About Loyola University Health System
Loyola University Health System (LUHS) is part of Trinity Health. Based in the western suburbs of Chicago, LUHS is a quaternary care system with a 61-acre main medical center campus, the 36-acre Gottlieb Memorial Hospital campus and more than 30 primary and specialty care facilities in Cook, Will and DuPage counties. Loyola University Medical Center’s campus is conveniently located in Maywood, 13 miles west of Chicago’s Loop and 8 miles east of Oak Brook, Ill. At the heart of the medical center campus is a 559-licensed-bed hospital that houses a Level 1 Trauma Center, a Burn Center and the Ronald McDonald® Children's Hospital of Loyola University Medical Center. Also on campus are the Cardinal Bernardin Cancer Center, Loyola Outpatient Center, Center for Heart & Vascular Medicine and Loyola Oral Health Center as well as Loyola University Chicago Stritch School of Medicine, Loyola University Chicago Marcella Niehoff School of Nursing and the Loyola Center for Fitness. Loyola's Gottlieb campus in Melrose Park includes the 255-licensed-bed community hospital, the Professional Office Building housing 150 private practice clinics, the Adult Day Care, the Gottlieb Center for Fitness, Loyola Center for Metabolic Surgery and Bariatric Care and the Loyola Cancer Care & Research at the Marjorie G. Weinberg Cancer Center at Melrose Park.
Trinity Health is a national Catholic health system with an enduring legacy and a steadfast mission to be a transforming and healing presence within the communities we serve. Trinity is committed to being a people-centered health care system that enables better health, better care and lower costs. Trinity Health has 88 hospitals and hundreds of continuing care facilities, home care agencies and outpatient centers in 21 states and 119,000 employees.