Toni Pak, PhD | Loyola Medicine

Toni Pak, PhD

Cell and Molecular Physiology

Professor
Department Chairperson, Cell and Molecular Physiology

Languages Spoken

English

Clinical Expertise

Biography

Interests

Medical Education

Medical School
Residency
Fellowship

Board Certification

Research

  • 17beta-estradiol regulates the RNA-binding protein Nova1 which then regulates the alternative splicing of estrogen receptor beta in the aging female rat brain, Shults, C. L.; Dingwall, C. B.; Kim, C. K.; Pinceti, E.; Rao, Y. S.; Pak, T. R., Neurobiology of aging
  • Binge Drinking and Intergenerational Implications: Parental Preconception Alcohol Impacts Offspring Development in Rats. Asimes, A; Kim, CK; Cuarenta, A; Auger, AP; Pak, TR, Journal of the Endocrine Society
  • Adolescent binge alcohol exposure increases risk assessment behaviors in male Wistar rats after exposure to an acute psychological stressor in adulthood Torcaso, A.; Asimes, A.; Meagher, M.; Pak, T. R., Psychoneuroendocrinology
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  • Adolescent binge-pattern alcohol exposure alters genome-wide DNA methylation patterns in the hypothalamus of alcohol-naive male offspring Asimes, A.; Torcaso, A.; Pinceti, E.; Kim, C. K.; Zeleznik-Le, N. J.; Pak, T. R., Alcohol (Fayetteville, N.Y.)
  • Structural and functional characteristics of estrogen receptor beta (ERbeta) splice variants: implications for the aging brain Kim, C. K.; Torcaso, A.; Asimes, A.; Chung, W. C. J.; Pak, T. R., Journal of neuroendocrinology
  • Differential Effects of E2 on MAPK Activity in the Brain and Heart of Aged Female Rats Pinceti, E.; Shults, C. L.; Rao, Y. S.; Pak, T. R., PLoS ONE
  • microRNAs and the adolescent brain: Filling the knowledge gap Rao, Y. S.; Pak, T. R., Neuroscience and biobehavioral reviews
  • Aging and Loss of Circulating 17beta-Estradiol Alters the Alternative Splicing of ERbeta in the Female Rat Brain Shults, C. L.; Pinceti, E.; Rao, Y. S.; Pak, T. R., Endocrinology
  • Phosphorylation alters Oestrogen Receptor beta-mediated transcription in neurons Pinceti, E.; Shults, C. L.; Rao, Y. S.; Mott, N. N.; Pak, T. R., Journal of neuroendocrinology
  • Prolonged ovarian hormone deprivation alters the effects of 17beta-estradiol on microRNA expression in the aged female rat hypothalamus Rao, Y. S.; Shults, C. L.; Pinceti, E.; Pak, T. R., Oncotarget
  • Age-dependent Effects of 17beta-estradiol on the dynamics of estrogen receptor beta (ERbeta) protein-protein interactions in the ventral hippocampus Mott, N. N.; Pinceti, E.; Rao, Y. S.; Przybycien-Szymanska, M. M.; Prins, S. A.; Shults, C. L.; Yang, X.; Glucksman, M. J.; Roberts, J. L.; Pak, T. R., Molecular & cellular proteomics : MCP
  • Long-Term Effects of Peripubertal Binge EtOH Exposure on Hippocampal microRNA Expression in the Rat Prins, S. A.; Przybycien-Szymanska, M. M.; Rao, Y. S.; Pak, T. R., PLoS ONE
  • Parental binge alcohol abuse alters f1 generation hypothalamic gene expression in the absence of direct fetal alcohol exposure Przybycien-Szymanska, M. M.; Rao, Y. S.; Prins, S. A.; Pak, T. R., PLoS ONE
  • An emerging role for microRNAs in sexually dimorphic neurobiological systems Pak, T. R.; Rao, Y. S.; Prins, S. A.; Mott, N. N., Pflugers Archiv : European journal of physiology
  • Effect of repetitive daily ethanol intoxication on adult rat brain: significant changes in phospholipase A2 enzyme levels in association with increased PARP-1 indicate neuroinflammatory pathway activation Tajuddin, N. F.; Przybycien-Szymanska, M. M.; Pak, T. R.; Neafsey, E. J.; Collins, M. A., Alcohol (Fayetteville, N.Y.)
  • Estrogen signaling and the aging brain: context-dependent considerations for postmenopausal hormone therapy Mott, N. N.; Pak, T. R., ISRN endocrinology
  • MicroRNAs in the aging female brain: a putative mechanism for age-specific estrogen effects Rao, Y. S.; Mott, N. N.; Wang, Y.; Chung, W. C.; Pak, T. R., Endocrinology
  • Sex differences in health and disease: brain and heart connections--a special issue Wattanapermpool, J.; de Tombe, P. P.; Pak, T. R., Pflugers Archiv : European journal of physiology
  • 17beta-Estradiol is required for the sexually dimorphic effects of repeated binge-pattern alcohol exposure on the HPA axis during adolescence. Przybycien-Szymanska, M. M.; Gillespie, R. A.; Pak, T. R., PLoS ONE [Electronic Resource]
  • Binge-pattern alcohol exposure during puberty induces long-term changes in HPA axis reactivity. Przybycien-Szymanska, M. M.; Mott, N. N.; Paul, C. R.; Gillespie, R. A.; Pak, T. R., PLoS ONE [Electronic Resource]
  • Effects of kisspeptin on parameters of the HPA axis. Rao, Y. S.; Mott, N. N.; Pak, T. R., Endocrine
  • Binge-pattern alcohol exposure during puberty induces sexually dimorphic changes in genes regulating the HPA axis. Przybycien-Szymanska, M. M.; Rao, Y. S.; Pak, T. R., American Journal of Physiology - Endocrinology & Metabolism
  • Differential fibroblast growth factor 8 (FGF8)-mediated autoregulation of its cognate receptors Fgfr1 and Fgfr3, in neuronal cell lines., Mott, N. N.; Chung, W. C.; Tsai, P. S.; Pak, T. R., PLoS ONE [Electronic Resource]
  • Arginine vasopressin regulation in pre- and postpubertal male rats by the androgen metabolite 3beta-diol. Pak, T. R.; Chung, W. C.; Hinds, L. R.; Handa, R. J., American Journal of Physiology - Endocrinology & Metabolism