Seth Robia, PhD

Cell and Molecular Physiology

Associate Professor
Co-Director, Cardiovascular Research Institute, Program Director, Advanced Non-Linear Imaging

Languages Spoken

English

Research

  • A Structural Mechanism for Calcium Transporter Headpiece Closure Smolin, N.; Robia, S. L., The journal of physical chemistry.B
  • ABC Transporter Structure Changes Detected by Intramolecular Fluorescence Energy Transfer for High-throughput Screening Iram, S. H.; Gruber, S. J.; Raguimova, O. N.; Thomas, D. D.; Robia, S. L., Molecular pharmacology
  • Acute Inotropic and Lusitropic Effects of Cardiomyopathic R9C Mutation of Phospholamban Abrol, N.; de Tombe, P. P.; Robia, S. L., The Journal of biological chemistry
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  • ATP-Binding Cassette Transporter Structure Changes Detected by Intramolecular Fluorescence Energy Transfer for High-Throughput Screening Iram, S. H.; Gruber, S. J.; Raguimova, O. N.; Thomas, D. D.; Robia, S. L., Molecular pharmacology
  • Rheostatic Regulation of the SERCA/Phospholamban Membrane Protein Complex Using Non-Coding RNA and Single-Stranded DNA oligonucleotides Soller, K. J.; Verardi, R.; Jing, M.; Abrol, N.; Yang, J.; Walsh, N.; Vostrikov, V. V.; Robia, S. L.; Bowser, M. T.; Veglia, G., Scientific reports
  • Phospholamban C-terminal residues are critical determinants of the structure and function of the calcium ATPase regulatory complex Abrol, N.; Smolin, N.; Armanious, G.; Ceholski, D. K.; Trieber, C. A.; Young, H. S.; Robia, S. L., The Journal of biological chemistry
  • Restriction of HIV-1 by rhesus TRIM5alpha is governed by alpha helices in the Linker2 region Sastri, J.; Johnsen, L.; Smolin, N.; Imam, S.; Mukherjee, S.; Lukic, Z.; Brandariz-Nunez, A.; Robia, S. L.; Diaz-Griffero, F.; Wiethoff, C.; Campbell, E. M., Journal of virology
  • Phosphorylated Phospholamban Stabilizes a Compact Conformation of the Cardiac Calcium-ATPase Pallikkuth, S.; Blackwell, D. J.; Hu, Z.; Hou, Z.; Zieman, D. T.; Svensson, B.; Thomas, D. D.; Robia, S. L., Biophysical journal
  • Dysferlin forms a dimer mediated by the C2 domains and the transmembrane domain in vitro and in living cells Xu, L.; Pallikkuth, S.; Hou, Z.; Mignery, G. A.; Robia, S. L.; Han, R., PLoS ONE
  • Focal adhesion kinase-related nonkinase inhibits vascular smooth muscle cell invasion by focal adhesion targeting tyrosine 168 phosphorylation, and competition for p130(Cas) binding., Koshman, Y. E.; Chu, M.; Engman, S. J.; Kim, T.; Iyengar, R.; Robia, S. L.; Samarel, A. M., Arteriosclerosis, Thrombosis & Vascular Biology
  • Phospholamban binds with differential affinity to calcium pump conformers. Bidwell, P.; Blackwell, D. J.; Hou, Z.; Zima, A. V.; Robia, S. L., Journal of Biological Chemistry
  • Phosphomimetic mutations enhance oligomerization of phospholemman and modulate its interaction with the Na/K-ATPase. Song, Q.; Pallikkuth, S.; Bossuyt, J.; Bers, D. M.; Robia, S. L., Journal of Biological Chemistry
  • TRIM5alpha associates with proteasomal subunits in cells while in complex with HIV-1 virions Lukic, Z.; Hausmann, S.; Sebastian, S.; Rucci, J.; Sastri, J.; Robia, S. L.; Luban, J.; Campbell, E. M., Retrovirology
  • FRNK inhibition of focal adhesion kinase-dependent signaling and migration in vascular smooth muscle cells. Koshman, Y. E.; Kim, T.; Chu, M.; Engman, S. J.; Iyengar, R.; Robia, S. L.; Samarel, A. M., Arteriosclerosis, Thrombosis & Vascular Biology
  • p62/sequestosome-1 associates with and sustains the expression of retroviral restriction factor TRIM5alpha. O'Connor, C.; Pertel, T.; Gray, S.; Robia, S. L.; Bakowska, J. C.; Luban, J.; Campbell, E. M., Journal of virology
  • Isoform specificity of the Na/K-ATPase association and regulation by phospholemman. Bossuyt, J.; Despa, S.; Han, F.; Hou, Z.; Robia, S. L.; Lingrel, J. B.; Bers, D. M., Journal of Biological Chemistry
  • The E3 ubiquitin ligase atrophin interacting protein 4 binds directly to the chemokine receptor CXCR4 via a novel WW domain-mediated interaction. Bhandari, D.; Robia, S. L.; Marchese, A., Molecular biology of the cell
  • Phospholamban oligomerization quaternary structure, and sarco(endo)plasmic reticulum calcium ATPase binding measured by fluorescence resonance energy transfer in living cells., Kelly, E. M.; Hou, Z.; Bossuyt, J.; Bers, D. M.; Robia, S. L., Journal of Biological Chemistry
  • Phosphomimetic mutations increase phospholamban oligomerization and alter the structure of its regulatory complex. Hou, Z.; Kelly, E. M.; Robia, S. L., Journal of Biological Chemistry
  • Forster transfer recovery reveals that phospholamban exchanges slowly from pentamers but rapidly from the SERCA regulatory complex. Robia, S. L.; Campbell, K. S.; Kelly, E. M.; Hou, Z.; Winters, D. L.; Thomas, D. D., Circulation research