Scott Smith, MD, PhD, FACP

Medicine

Hematology/Oncology
Professor

Languages Spoken

English

Clinical Expertise

  • Bone Marrow Disorders
  • Leukemia
  • Non-Hodgkin's Lymphoma
  • Refractory Lymphoma
  • Relapsed Lymphoma

About Dr. Smith

Interests
Fly Fishing, Mountain Biking, Hiking, Reading, Golf

Medical Education

Medical School
Wayne State University School of Medicine
Residency
Loyola University Medical Center - Internal Medicine: General
Fellowship
Loyola University Medical Center - Hematology/Oncology

Board Certification

Hematology
American Board of Internal Medicine Subspecialty

  • Outbreak of Gastroenteritis in Adults Due to Rotavirus Genotype G12P[8 Pacilli, M.; Cortese, M. M.; Smith, S.; Siston, A.; Samala, U.; Bowen, M. D.; Parada, J. P.; Tam, K. I.; Rungsrisuriyachai, K.; Roy, S.; Esona, M. D.; Black, S. R., Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • Brentuximab vedotin in patients aged 60 years or older with relapsed or refractory CD30-positive lymphomas: a retrospective evaluation of safety and efficacy Gopal, A. K.; Bartlett, N. L.; Forero-Torres, A.; Younes, A.; Chen, R.; Friedberg, J. W.; Matous, J. V.; Shustov, A. R.; Smith, S. E.; Zain, J.; O'Meara, M. M.; Fanale, M. A., Leukemia & lymphoma
  • Durable remissions in a pivotal phase 2 study of brentuximab vedotin in relapsed or refractory Hodgkin lymphoma Gopal, A. K.; Chen, R.; Smith, S. E.; Ansell, S. M.; Rosenblatt, J. D.; Savage, K. J.; Connors, J. M.; Engert, A.; Larsen, E. K.; Chi, X.; Sievers, E. L.; Younes, A., Blood
  • Impact of induction regimen and stem cell transplantation on outcomes in double-hit lymphoma: a multicenter retrospective analysis Petrich, A. M.; Gandhi, M.; Jovanovic, B.; Castillo, J. J.; Rajguru, S.; Yang, D. T.; Shah, K. A.; Whyman, J. D.; Lansigan, F.; Hernandez-Ilizaliturri, F. J.; Lee, L. X.; Barta, S. K.; Melinamani, S.; Karmali, R.; Adeimy, C.; Smith, S.; Dalal, N.; Nabhan, C.; Peace, D.; Vose, J.; Evens, A. M.; Shah, N.; Fenske, T. S.; Zelenetz, A. D.; Landsburg, D. J.; Howlett, C.; Mato, A.; Jaglal, M.; Chavez, J. C.; Tsai, J. P.; Reddy, N.; Li, S.; Handler, C.; Flowers, C. R.; Cohen, J. B.; Blum, K. A.; Song, K.; Sun, H. L.; Press, O.; Cassaday, R.; Jaso, J.; Medeiros, L. J.; Sohani, A. R.; Abramson, J. S., Blood
  • Phase II study of the oral MEK inhibitor selumetinib in advanced acute myelogenous leukemia: a University of Chicago phase II consortium trial Jain, N.; Curran, E.; Iyengar, N. M.; Diaz-Flores, E.; Kunnavakkam, R.; Popplewell, L.; Kirschbaum, M. H.; Karrison, T.; Erba, H. P.; Green, M.; Poire, X.; Koval, G.; Shannon, K.; Reddy, P. L.; Joseph, L.; Atallah, E. L.; Dy, P.; Thomas, S. P.; Smith, S. E.; Doyle, L. A.; Stadler, W. M.; Larson, R. A.; Stock, W.; Odenike, O., Clinical cancer research : an official journal of the American Association for Cancer Research
  • Retreatment with brentuximab vedotin in patients with CD30-positive hematologic malignancies Bartlett, N. L.; Chen, R.; Fanale, M. A.; Brice, P.; Gopal, A.; Smith, S. E.; Advani, R.; Matous, J. V.; Ramchandren, R.; Rosenblatt, J. D.; Huebner, D.; Levine, P.; Grove, L.; Forero-Torres, A., Journal of hematology & oncology
  • Seven-year follow-up of allogeneic transplant using BCNU etoposide, cytarabine and melphalan chemotherapy in patients with Hodgkin lymphoma after autograft failure: importance of minimal residual disease, Sobol, U.; Rodriguez, T.; Smith, S.; Go, A.; Vimr, R.; Parthasarathy, M.; Guo, R.; Stiff, P., Leukemia & lymphoma
  • Brentuximab vedotin does not cause clinically relevant QTc interval prolongation in patients with CD30-positive hematologic malignancies Han, T. H.; Chen, R.; Advani, R.; Berryman, R. B.; Smith, S. E.; Forero-Torres, A.; Rosenblatt, J. D.; Smith, M. R.; Zain, J.; Hunder, N. N.; Engert, A., CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • High-dose vincristine sulfate liposome injection for advanced relapsed, and refractory adult Philadelphia chromosome-negative acute lymphoblastic leukemia, O'Brien, S.; Schiller, G.; Lister, J.; Damon, L.; Goldberg, S.; Aulitzky, W.; Ben-Yehuda, D.; Stock, W.; Coutre, S.; Douer, D.; Heffner, L. T.; Larson, M.; Seiter, K.; Smith, S.; Assouline, S.; Kuriakose, P.; Maness, L.; Nagler, A.; Rowe, J.; Schaich, M.; Shpilberg, O.; Yee, K.; Schmieder, G.; Silverman, J. A.; Thomas, D.; Deitcher, S. R.; Kantarjian, H., Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • Imbalance between neutrophil elastase and its inhibitor alpha1-antitrypsin in obesity alters insulin sensitivity inflammation, and energy expenditure, Mansuy-Aubert, V.; Zhou, Q. L.; Xie, X.; Gong, Z.; Huang, J. Y.; Khan, A. R.; Aubert, G.; Candelaria, K.; Thomas, S.; Shin, D. J.; Booth, S.; Baig, S. M.; Bilal, A.; Hwang, D.; Zhang, H.; Lovell-Badge, R.; Smith, S. R.; Awan, F. R.; Jiang, Z. Y., Cell metabolism
  • Marginal zone lymphoma of the thoracic dura causing spinal cord compression Dey, M.; Daniel, S.; Wong, R. H.; Smith, S. M.; Yamini, B., Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • Prevention of nausea and vomiting associated with stem cell transplant: results of a prospective randomized trial of aprepitant used with highly emetogenic preparative regimens, Stiff, P. J.; Fox-Geiman, M. P.; Kiley, K.; Rychlik, K.; Parthasarathy, M.; Fletcher-Gonzalez, D.; Porter, N.; Go, A.; Smith, S. E.; Rodriguez, T. E., Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
  • A phase 2 randomized multicenter study of 2 extended dosing schedules of oral ezatiostat in low to intermediate-1 risk myelodysplastic syndrome Raza, A.; Galili, N.; Smith, S. E.; Godwin, J.; Boccia, R. V.; Myint, H.; Mahadevan, D.; Mulford, D.; Rarick, M.; Brown, G. L.; Schaar, D.; Faderl, S.; Komrokji, R. S.; List, A. F.; Sekeres, M., Cancer
  • A retrospective multicenter analysis of elderly Hodgkin lymphoma: outcomes and prognostic factors in the modern era Evens, A. M.; Helenowski, I.; Ramsdale, E.; Nabhan, C.; Karmali, R.; Hanson, B.; Parsons, B.; Smith, S.; Larsen, A.; McKoy, J. M.; Jovanovic, B.; Gregory, S.; Gordon, L. I.; Smith, S. M., Blood
  • A retrospective multicenter analysis of elderly Hodgkin lymphoma: outcomes and prognostic factors in the modern era Evens, A. M.; Helenowski, I.; Ramsdale, E.; Nabhan, C.; Karmali, R.; Hanson, B.; Parsons, B.; Smith, S.; Larsen, A.; McKoy, J. M.; Jovanovic, B.; Gregory, S.; Gordon, L. I.; Smith, S. M., Blood
  • Analysis of very elderly (>/=80 years) non-hodgkin lymphoma: impact of functional status and co-morbidities on outcome Nabhan, C.; Smith, S. M.; Helenowski, I.; Ramsdale, E.; Parsons, B.; Karmali, R.; Feliciano, J.; Hanson, B.; Smith, S.; McKoy, J.; Larsen, A.; Hantel, A.; Gregory, S.; Evens, A. M., British journal of haematology
  • Analysis of very elderly (>/=80 years) non-hodgkin lymphoma: impact of functional status and co-morbidities on outcome Nabhan, C.; Smith, S. M.; Helenowski, I.; Ramsdale, E.; Parsons, B.; Karmali, R.; Feliciano, J.; Hanson, B.; Smith, S.; McKoy, J.; Larsen, A.; Hantel, A.; Gregory, S.; Evens, A. M., British journal of haematology
  • Phase 1 dose-ranging study of ezatiostat hydrochloride in combination with lenalidomide in patients with non-deletion (5q) low to intermediate-1 risk myelodysplastic syndrome (MDS) Raza, A.; Galili, N.; Mulford, D.; Smith, S. E.; Brown, G. L.; Steensma, D. P.; Lyons, R. M.; Boccia, R.; Sekeres, M. A.; Garcia-Manero, G.; Mesa, R. A., Journal of hematology & oncology
  • Results of a pivotal phase II study of brentuximab vedotin for patients with relapsed or refractory Hodgkin's lymphoma Younes, A.; Gopal, A. K.; Smith, S. E.; Ansell, S. M.; Rosenblatt, J. D.; Savage, K. J.; Ramchandren, R.; Bartlett, N. L.; Cheson, B. D.; de Vos, S.; Forero-Torres, A.; Moskowitz, C. H.; Connors, J. M.; Engert, A.; Larsen, E. K.; Kennedy, D. A.; Sievers, E. L.; Chen, R., Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • Safety and efficacy of brentuximab vedotin for Hodgkin lymphoma recurring after allogeneic stem cell transplantation Gopal, A. K.; Ramchandren, R.; O'Connor, O. A.; Berryman, R. B.; Advani, R. H.; Chen, R.; Smith, S. E.; Cooper, M.; Rothe, A.; Matous, J. V.; Grove, L. E.; Zain, J., Blood
  • Spontaneous regression of follicular dendritic cell sarcoma Caces, D. B.; Daniel, S.; Paredes-Tejada, J. M.; Smith, S., Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • TNF-inhibition with etanercept for graft-versus-host disease prevention in high-risk HCT: lower TNFR1 levels correlate with better outcomes Choi, S. W.; Stiff, P.; Cooke, K.; Ferrara, J. L.; Braun, T.; Kitko, C.; Reddy, P.; Yanik, G.; Mineishi, S.; Paczesny, S.; Hanauer, D.; Pawarode, A.; Peres, E.; Rodriguez, T.; Smith, S.; Levine, J. E., Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
  • Multicenter analysis of 80 solid organ transplantation recipients with post-transplantation lymphoproliferative disease: outcomes and prognostic factors in the modern era Evens, A. M.; David, K. A.; Helenowski, I.; Nelson, B.; Kaufman, D.; Kircher, S. M.; Gimelfarb, A.; Hattersley, E.; Mauro, L. A.; Jovanovic, B.; Chadburn, A.; Stiff, P.; Winter, J. N.; Mehta, J.; Van Besien, K.; Gregory, S.; Gordon, L. I.; Shammo, J. M.; Smith, S. E.; Smith, S. M., Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • Multicenter analysis of 80 solid organ transplantation recipients with post-transplantation lymphoproliferative disease: outcomes and prognostic factors in the modern era Evens, A. M.; David, K. A.; Helenowski, I.; Nelson, B.; Kaufman, D.; Kircher, S. M.; Gimelfarb, A.; Hattersley, E.; Mauro, L. A.; Jovanovic, B.; Chadburn, A.; Stiff, P.; Winter, J. N.; Mehta, J.; Van Besien, K.; Gregory, S.; Gordon, L. I.; Shammo, J. M.; Smith, S. E.; Smith, S. M., Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • Randomized phase III trial of pegfilgrastim versus filgrastim after autologus peripheral blood stem cell transplantation. Gerds, A.; Fox-Geiman, M.; Dawravoo, K.; Rodriguez, T.; Toor, A.; Smith, S.; Kiley, K.; Fletcher-Gonzalez, D.; Hicks, C.; Stiff, P., Biology of Blood & Marrow Transplantation
  • Temsirolimus has activity in non-mantle cell non-Hodgkin's lymphoma subtypes: The University of Chicago phase II consortium Smith, S. M.; van Besien, K.; Karrison, T.; Dancey, J.; McLaughlin, P.; Younes, A.; Smith, S.; Stiff, P.; Lester, E.; Modi, S.; Doyle, L. A.; Vokes, E. E.; Pro, B., Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • Temsirolimus has activity in non-mantle cell non-Hodgkin's lymphoma subtypes: The University of Chicago phase II consortium Smith, S. M.; van Besien, K.; Karrison, T.; Dancey, J.; McLaughlin, P.; Younes, A.; Smith, S.; Stiff, P.; Lester, E.; Modi, S.; Doyle, L. A.; Vokes, E. E.; Pro, B., Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • The impact of pharmacotherapy on depression and quality of life in patients undergoing a bone marrow transplant (BMT). Mumby, P. B.; Garcia, C.; Trivedi-Purohit, R.; Gourvitz, R.; Rychlik, K.; Rodriguez, T.; Smith, S. E.; Toor, A. A.; Rao, M.; Stiff, P. J., ASCO Meeting Abstracts
  • Chronic intermittent hypoxia increases left ventricular contractility in C57BL/6J mice Naghshin, J.; McGaffin, K. R.; Witham, W. G.; Mathier, M. A.; Romano, L. C.; Smith, S. H.; Janczewski, A. M.; Kirk, J. A.; Shroff, S. G.; O'Donnell, C. P., Journal of applied physiology (Bethesda, Md.: 1985)
  • Left ventricular and myocardial function in mice expressing constitutively pseudophosphorylated cardiac troponin I Kirk, J. A.; MacGowan, G. A.; Evans, C.; Smith, S. H.; Warren, C. M.; Mamidi, R.; Chandra, M.; Stewart, A. F.; Solaro, R. J.; Shroff, S. G., Circulation research
  • Phase 1 multicenter dose-escalation study of ezatiostat hydrochloride (TLK199 tablets) a novel glutathione analog prodrug, in patients with myelodysplastic syndrome, Raza, A.; Galili, N.; Smith, S.; Godwin, J.; Lancet, J.; Melchert, M.; Jones, M.; Keck, J. G.; Meng, L.; Brown, G. L.; List, A., Blood
  • A single-institution experience with the AneuRx Stent Graft for endovascular repair of abdominal aortic aneurysm. Smith, S.; Mountcastle, S.; Burridge, A.; Dodson, T. F.; Salam, A. A.; Kasirajan, K.; Milner, R.; Veeraswamy, R.; Chaikof, E. L., Annals of Vascular Surgery
  • Feasibility of conditioning with thymoglobulin and reduced intensity TBI to reduce acute GVHD in recipients of allogeneic SCT Toor, A.; Rodriguez, T.; Bauml, M.; Mathews, H.; Shanti, S.; Senitzer, D.; Kini, A.; Norton, J.; Parthasarathy, M.; Mohideen, N.; Petrowsky, C.; Bonilla, B.; Smith, S.; Stiff, P., Bone marrow transplantation
  • Hydroxyurea azacitidine and gemtuzumab ozogamicin therapy in patients with previously untreated non-M3 acute myeloid leukemia and high-risk myelodysplastic syndromes in the elderly: results from a pilot trial, Nand, S.; Godwin, J.; Smith, S.; Barton, K.; Michaelis, L.; Alkan, S.; Veerappan, R.; Rychlik, K.; Germano, E.; Stiff, P., Leukemia & lymphoma
  • Sonographic appearance of ruptured ovarian cyst in the neonatal period. Gallagher, T. A.; Lim-Dunham, J. E.; Vade, A.; Smith, S.; Salhadar, A.; Ward, K. A., Journal of Clinical Ultrasound
  • The Curriculum for the Hospitalized Aging Medical Patient program: a collaborative faculty development program for hospitalists general internists, and geriatricians., Podrazik, P. M.; Levine, S.; Smith, S.; Scott, D.; Dubeau, C. E.; Baron, A.; Whelan, C.; Johnson, J.; Cook, S.; Arora, V.; Meltzer, D.; Sachs, G., Journal of Hospital Medicine (Online)
  • Volvox species in the Pap test of a 24-year-old female. Vasquez, J. B.; Smith, S. V.; Thomas, R.; Yong, S. L.; Wojcik, E. M., Diagnostic cytopathology
  • Donor polymorphisms in Toll-like receptor-4 influence the development of rejection after renal transplantation. Palmer, S. M.; Burch, L. H.; Mir, S.; Smith, S. R.; Kuo, P. C.; Herczyk, W. F.; Reinsmoen, N. L.; Schwartz, D. A., Clinical transplantation
  • The administration of polymerized human hemoglobin (Pyridoxylated) to a Jehovah's Witness after submyeloablative stem cell transplantation complicated by delayed graft failure Smith, S. E.; Toor, A.; Rodriguez, T.; Stiff, P., Comprehensive therapy
  • Discovering the full spectrum of cardiovascular disease: Minority Health Summit 2003: report of the Obesity Metabolic Syndrome, and Hypertension Writing Group., Smith, S. C., Jr.; Clark, L. T.; Daniels, S. R.; Kumanyika, S. K.; Ofili, E.; Quinones, M. A.; Sanchez, E. J.; Saunders, E.; Tiukinhoy, S. D., Circulation
  • Megakaryoblastic leukemia with involvement of the pleural fluid. Farray, D.; Al-Masri, H.; Hattersley, E.; Smith, S. E., American Journal of Hematology
  • Obesity predicts increased overall complications following pancreas transplantation. Hanish, S. I.; Petersen, R. P.; Collins, B. H.; Tuttle-Newhall, J.; Marroquin, C. E.; Kuo, P. C.; Butterly, D. W.; Smith, S. R.; Desai, D. M., Transplantation proceedings
  • 15th Annual Spring Brain Conference March 10-13, 2004, summary report., Anstrom, K.; Bergles, D.; Bradley, K.; Cao, Y.; Cestnick, L.; Lee, S.; Piedras-Renteria, E. S.; Savoie, K.; Smith, S. M., Somatosensory & motor research
  • The signal from the initiation of meiotic recombination to the first division of meiosis Malone, R. E.; Haring, S. J.; Foreman, K. E.; Pansegrau, M. L.; Smith, S. M.; Houdek, D. R.; Carpp, L.; Shah, B.; Lee, K. E., Eukaryotic cell
  • Acute myeloid leukemia in the older patient Godwin, J. E.; Smith, S. E., Critical Reviews in Oncology-Hematology
  • Beneficial effect of plasmapheresis and intravenous immunoglobulin on renal allograft survival of patients with acute humoral rejection. Rocha, P. N.; Butterly, D. W.; Greenberg, A.; Reddan, D. N.; Tuttle-Newhall, J.; Collins, B. H.; Kuo, P. C.; Reinsmoen, N.; Fields, T.; Howell, D. N.; Smith, S. R., Transplantation