Richard Kennedy, PhD

Cell and Molecular Physiology

Molecular Pharmacology and Therapeutics
Lecturer

Languages Spoken

English

Biography

Interests
Fishing, Jogging

Medical Education

Board Certification

American Nurses Credentialing Center
Anesthesiology
American Board of

Research

  • Effects of a caspase and a calpain inhibitor on resting energy expenditures in normal and hypermetabolic rats: a pilot study Vana, P. G.; LaPorte, H. M.; Kennedy, R. H.; Gamelli, R. L.; Majetschak, M., Physiological Research / Academia Scientiarum Bohemoslovaca
  • Effects of Mesalamine Treatment on Gut Barrier Integrity After Burn Injury Cannon, A. R.; Akhtar, S.; Hammer, A. M.; Morris, N. L.; Javorski, M. J.; Li, X.; Kennedy, R. H.; Gamelli, R. L.; Choudhry, M. A., Journal of burn care & research : official publication of the American Burn Association
  • Burn Injury Alters the Intestinal Microbiome and Increases Gut Permeability and Bacterial Translocation Earley, Z. M.; Akhtar, S.; Green, S. J.; Naqib, A.; Khan, O.; Cannon, A. R.; Hammer, A. M.; Morris, N. L.; Li, X.; Eberhardt, J. M.; Gamelli, R. L.; Kennedy, R. H.; Choudhry, M. A., PLoS ONE
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  • Mesh wrapping for severe hepatic injury: a beneficial option in the trauma surgeon's armamentarium Kennedy, R.; Brevard, S. B.; Bosarge, P.; Simmons, J. D.; Frotan, M. A.; Baker, J. A.; Tuart, L.; Pritchett, C.; Gonzalez, R. P., American Journal of Surgery
  • Proteasome Inhibition After Burn Injury Vana, P. G.; LaPorte, H. M.; Wong, Y. M.; Kennedy, R. H.; Gamelli, R. L.; Majetschak, M., Journal of burn care & research : official publication of the American Burn Association
  • Activities of nonlysosomal proteolytic systems in skeletal and cardiac muscle during burn-induced hypermetabolism Wong, Y. M.; La Porte, H. M.; Szilagyi, A.; Bach, H. H., 4th; Ke-He, L.; Kennedy, R. H.; Gamelli, R. L.; Shankar, R.; Majetschak, M., Journal of burn care & research : official publication of the American Burn Association
  • CAPriCORN: Chicago Area Patient-Centered Outcomes Research Network Kho, A. N.; Hynes, D. M.; Goel, S.; Solomonides, A. E.; Price, R.; Hota, B.; Sims, S. A.; Bahroos, N.; Angulo, F.; Trick, W. E.; Tarlov, E.; Rachman, F. D.; Hamilton, A.; Kaleba, E. O.; Badlani, S.; Volchenboum, S. L.; Silverstein, J. C.; Tobin, J. N.; Schwartz, M. A.; Levine, D.; Wong, J. B.; Kennedy, R. H.; Krishnan, J. A.; Meltzer, D. O.; Collins, J. M.; Mazany, T.; CAPriCORN Team, Journal of the American Medical Informatics Association : JAMIA
  • Cardiac dysfunction subsequent to chronic ozone exposure in rats Perepu, R. S.; Dostal, D. E.; Garcia, C.; Kennedy, R. H.; Sethi, R., MOLECULAR AND CELLULAR BIOCHEMISTRY
  • The novel antibacterial drug XF-70 is a potent inhibitor of Staphylococcus aureus infection of the burn wound. Hurtuk, M. G.; He, L. K.; Szilagyi, A.; Gamelli, R. L.; Hecht, D. W.; Kennedy, R. H.; Rhys-Williams, W.; Love, W. G.; Shankar, R., Journal of Burn Care & Research
  • Effect of anti-oxidant treatment on hyperhomocysteinemia-induced myocardial fibrosis and diastolic dysfunction Joseph, J.; Joseph, L.; Devi, S.; Kennedy, R. H., The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
  • Influence of endothelin 1 receptor inhibition on functional structural and molecular changes in the rat heart after irradiation, Boerma, M.; Wang, J.; Kulkarni, A.; Roberto, K. A.; Qiu, X.; Kennedy, R. H.; Hauer-Jensen, M., Radiation research
  • Acute dilatory and negative inotropic effects of homocysteine are inhibited by an adenosine blocker. Kennedy, R. H.; Owings, R.; Joseph, J.; Melchert, R. B.; Hauer-Jensen, M.; Boerma, M., Clinical & Experimental Pharmacology & Physiology
  • Cardiovascular effects of hyperhomocysteinemia in conscious unrestrained rats. Kennedy, R. H.; Melchert, R. B.; Joseph, J., American Journal of Hypertension
  • Effect of long-term hyperhomocysteinemia on myocardial structure and function in hypertensive rats. Devi, S.; Kennedy, R. H.; Joseph, L.; Shekhawat, N. S.; Melchert, R. B.; Joseph, J., Cardiovascular Pathology
  • TNF-alpha-induced impairment of mitochondrial integrity and apoptosis mediated by caspase-8 in adult ventricular myocytes. Zhu, J.; Liu, M.; Kennedy, R. H.; Liu, S. J., Cytokine
  • Both cGMP and peroxynitrite mediate chronic interleukin-6-induced negative inotropy in adult rat ventricular myocytes. Yu, X. W.; Liu, M. Y.; Kennedy, R. H.; Liu, S. J., Journal of Physiology
  • Cardiac function in hearts isolated from a rat model deficient in mast cells. Kennedy, R. H.; Hauer-Jensen, M.; Joseph, J., American Journal of Physiology - Heart & Circulatory Physiology
  • Contribution of de novo point mutations to the overall mutational burden in mitochondrial DNA of adult rats. Khaidakov, M.; Chavannes-Turesky, N.; Cooney, C. A.; Dupont-Versteegden, E. E.; Kennedy, R. H.; Siegel, E. R.; Khaidakova, G.; Shmookler Reis, R. J., Experimental gerontology
  • Deoxycholyltaurine-induced vasodilation of rodent aorta is nitric oxide- and muscarinic M(3) receptor-dependent. Khurana, S.; Yamada, M.; Wess, J.; Kennedy, R. H.; Raufman, J. P., European journal of pharmacology
  • Gender differences in blood pressure and heart rate in spontaneously hypertensive and Wistar-Kyoto rats. Maris, M. E.; Melchert, R. B.; Joseph, J.; Kennedy, R. H., Clinical & Experimental Pharmacology & Physiology
  • Influence of mast cells on structural and functional manifestations of radiation-induced heart disease. Boerma, M.; Wang, J.; Wondergem, J.; Joseph, J.; Qiu, X.; Kennedy, R. H.; Hauer-Jensen, M., Cancer research
  • Inhibition of sarcoplasmic reticular function by chronic interleukin-6 exposure via iNOS in adult ventricular myocytes. Yu, X. W.; Chen, Q.; Kennedy, R. H.; Liu, S. J., Journal of Physiology
  • Protective role of mast cells in homocysteine-induced cardiac remodeling. Joseph, J.; Kennedy, R. H.; Devi, S.; Wang, J.; Joseph, L.; Hauer-Jensen, M., American Journal of Physiology - Heart & Circulatory Physiology
  • Acute negative inotropic effects of homocysteine are mediated via the endothelium. Kennedy, R. H.; Owings, R.; Shekhawat, N.; Joseph, J., American Journal of Physiology - Heart & Circulatory Physiology
  • Hyperhomocysteinaemia-induced atrial remodelling in hypertensive rats. Joseph, J.; Washington, A.; Joseph, L.; Kennedy, R. H., Clinical & Experimental Pharmacology & Physiology
  • Vasodilatory effects of cholinergic agonists are greatly diminished in aorta from M3R-/- mice. Khurana, S.; Chacon, I.; Xie, G.; Yamada, M.; Wess, J.; Raufman, J. P.; Kennedy, R. H., European journal of pharmacology
  • Alterations in Ca2+ cycling by lysoplasmenylcholine in adult rabbit ventricular myocytes Liu, S. J.; Kennedy, R. H.; Creer, M. H.; McHowat, J., American journal of physiology.Cell physiology
  • Hyperhomocysteinemia leads to pathological ventricular hypertrophy in normotensive rats Joseph, J.; Joseph, L.; Shekhawat, N. S.; Devi, S.; Wang, J.; Melchert, R. B.; Hauer-Jensen, M.; Kennedy, R. H., American journal of physiology.Heart and circulatory physiology
  • JAK2/STAT3 not ERK1/2, mediates interleukin-6-induced activation of inducible nitric-oxide synthase and decrease in contractility of adult ventricular myocytes, Yu, X.; Kennedy, R. H.; Liu, S. J., The Journal of biological chemistry
  • Positive inotropic effect of ceramide in adult ventricular myocytes: mechanisms dissociated from its reduction in Ca2+ influx Liu, S. J.; Kennedy, R. H., American journal of physiology.Heart and circulatory physiology
  • Sex differences in L-type calcium current after chronic ethanol consumption in rats Kennedy, R. H.; Liu, S. J., Toxicology and applied pharmacology
  • Effects of gender on the cardiac toxicity elicited by chronic ethanol intake in rats Kennedy, R. H.; Stewart, C.; Light, K. E.; Wyeth, R. P., Toxicology and applied pharmacology
  • Hyperhomocysteinemia leads to adverse cardiac remodeling in hypertensive rats Joseph, J.; Washington, A.; Joseph, L.; Koehler, L.; Fink, L. M.; Hauer-Jensen, M.; Kennedy, R. H., American journal of physiology.Heart and circulatory physiology
  • Linoleic acid metabolites act to increase contractility in isolated rat heart Mitchell, L. A.; Grant, D. F.; Melchert, R. B.; Petty, N. M.; Kennedy, R. H., CARDIOVASCULAR TOXICOLOGY
  • Lithocholylcholine a bile acid/acetylcholine hybrid, is a muscarinic receptor antagonist, Cheng, K.; Khurana, S.; Chen, Y.; Kennedy, R. H.; Zimniak, P.; Raufman, J. P., The Journal of pharmacology and experimental therapeutics
  • The stimulation of tumor necrosis factor and inhibition of glucose transport and lipoprotein lipase in adipose cells by 2 3, 7, 8-tetrachlorodibenzo-p-dioxin, Kern, P. A.; Dicker-Brown, A.; Said, S. T.; Kennedy, R. H.; Fonseca, V. A., Metabolism: clinical and experimental
  • Doxorubicin affects the cardiac muscarinic system in the rat Chugun, A.; Uchide, T.; Temma, K.; Kennedy, R. H.; Klimberg, S. V.; Hara, Y.; Sasaki, T.; Akera, T., The Journal of veterinary medical science / the Japanese Society of Veterinary Science
  • Lovastatin inhibits phenylephrine-induced ERK activation and growth of cardiac Melchert, R. B.; Liu, H.; Granberry, M. C.; Kennedy, R. H., CARDIOVASCULAR TOXICOLOGY
  • Aging-associated changes in whole cell K(+) and L-type Ca(2+) currents in rat ventricular myocytes Liu, S. J.; Wyeth, R. P.; Melchert, R. B.; Kennedy, R. H., American journal of physiology.Heart and circulatory physiology
  • Exposure to 2 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) is associated with hyperinsulinemia and insulin resistance, Cranmer, M.; Louie, S.; Kennedy, R. H.; Kern, P. A.; Fonseca, V. A., Toxicological sciences : an official journal of the Society of Toxicology
  • Induction of Ca-independent PLA(2) and conservation of plasmalogen polyunsaturated fatty acids in diabetic heart McHowat, J.; Creer, M. H.; Hicks, K. K.; Jones, J. H.; McCrory, R.; Kennedy, R. H., American journal of physiology.Endocrinology and metabolism