Gregory Mignery, PhD

Cell and Molecular Physiology

Professor

Languages Spoken

English

Biography

Interests
Astronomy, Camping, Paleontology

Medical Education

Fellowship
University of Texas Southwestern Medical Center - Research

Research

  • Calcineurin-NFATc regulates type 2 inositol 1 4, 5-trisphosphate receptor (InsP3R2) expression during cardiac remodeling, Sankar, N.; deTombe, P. P.; Mignery, G. A., The Journal of biological chemistry
  • Spatially Defined InsP3-Mediated Signaling in Embryonic Stem Cell-Derived Cardiomyocytes Kapoor, N.; Maxwell, J. T.; Mignery, G. A.; Will, D.; Blatter, L. A.; Banach, K., PLoS ONE
  • Dysferlin forms a dimer mediated by the C2 domains and the transmembrane domain in vitro and in living cells Xu, L.; Pallikkuth, S.; Hou, Z.; Mignery, G. A.; Robia, S. L.; Han, R., PLoS ONE
View All ResearchShow Less
  • IP3 receptor-dependent Ca2+ release modulates excitation-contraction coupling in rabbit ventricular myocytes Domeier, T. L.; Zima, A. V.; Maxwell, J. T.; Huke, S.; Mignery, G. A.; Blatter, L. A., American Journal of Physiology - Heart & Circulatory Physiology
  • Cell cycle-dependent calcium oscillations in mouse embryonic stem cells. Kapur, N.; Mignery, G. A.; Banach, K., American Journal of Physiology - Cell Physiology
  • IP3-dependent nuclear Ca2+ signalling in the mammalian heart. Zima, A. V.; Bare, D. J.; Mignery, G. A.; Blatter, L. A., Journal of Physiology
  • Biosensors to measure inositol 1 4, 5-trisphosphate concentration in living cells with spatiotemporal resolution., Remus, T. P.; Zima, A. V.; Bossuyt, J.; Bare, D. J.; Martin, J. L.; Blatter, L. A.; Bers, D. M.; Mignery, G. A., Journal of Biological Chemistry
  • Cardiac type 2 inositol 1 4, 5-trisphosphate receptor: interaction and modulation by calcium/calmodulin-dependent protein kinase II., Bare, D. J.; Kettlun, C. S.; Liang, M.; Bers, D. M.; Mignery, G. A., Journal of Biological Chemistry
  • Expression of a truncated form of inositol 1 4, 5-trisphosphate receptor type III in the cytosol of DT40 triple inositol 1, 4, 5-trisphosphate receptor-knockout cells., Guillemette, J.; Caron, A. Z.; Regimbald-Dumas, Y.; Arguin, G.; Mignery, G. A.; Boulay, G.; Guillemette, G., Cell calcium
  • Bcl-2 functionally interacts with inositol 1 4, 5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1, 4, 5-trisphosphate., Chen, R.; Valencia, I.; Zhong, F.; McColl, K. S.; Roderick, H. L.; Bootman, M. D.; Berridge, M. J.; Conway, S. J.; Holmes, A. B.; Mignery, G. A.; Velez, P.; Distelhorst, C. W., Journal of Cell Biology
  • Erythropoietin-modulated calcium influx through TRPC2 is mediated by phospholipase Cgamma and IP3R. Tong, Q.; Chu, X.; Cheung, J. Y.; Conrad, K.; Stahl, R.; Barber, D. L.; Mignery, G.; Miller, B. A., American Journal of Physiology - Cell Physiology
  • Single channel function of inositol 1 4, 5-trisphosphate receptor type-1 and -2 isoform domain-swap chimeras., Ramos, J.; Jung, W.; Ramos-Franco, J.; Mignery, G. A.; Fill, M., Journal of General Physiology
  • Structure of the type 1 inositol 1 4, 5-trisphosphate receptor revealed by electron cryomicroscopy., Serysheva, I. I.; Bare, D. J.; Ludtke, S. J.; Kettlun, C. S.; Chiu, W.; Mignery, G. A., Journal of Biological Chemistry
  • Astrocytes in adult rat brain express type 2 inositol 1 4, 5-trisphosphate receptors., Holtzclaw, L. A.; Pandhit, S.; Bare, D. J.; Mignery, G. A.; Russell, J. T., Glia
  • Carboxyl-terminal sequences critical for inositol 1 4, 5-trisphosphate receptor subunit assembly., Galvan, D. L.; Mignery, G. A., Journal of Biological Chemistry
  • Protein kinase A phosphorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes. Li, Y.; Kranias, E. G.; Mignery, G. A.; Bers, D. M., Circulation research
  • Activation and propagation of Ca(2+) release during excitation-contraction coupling in atrial myocytes. Kockskamper, J.; Sheehan, K. A.; Bare, D. J.; Lipsius, S. L.; Mignery, G. A.; Blatter, L. A., Biophysical journal
  • Calcium transients in 1B5 myotubes lacking ryanodine receptors are related to inositol trisphosphate receptors. Estrada, M.; Cardenas, C.; Liberona, J. L.; Carrasco, M. A.; Mignery, G. A.; Allen, P. D.; Jaimovich, E., Journal of Biological Chemistry
  • Single-channel function of recombinant type 2 inositol 1 4, 5-trisphosphate receptor., Ramos-Franco, J.; Bare, D.; Caenepeel, S.; Nani, A.; Fill, M.; Mignery, G., Biophysical journal