Urologist: Gopal Gupta, MD, FACS | Loyola Medicine

Gopal Gupta, MD, FACS

Gopal Gupta, MD

Urology

Radiology
Associate Professor

Languages Spoken

English, Hindi,French

Clinical Expertise

  • Bladder Cancer
  • Kidney Cancer
  • Laparoscopy
  • Robotic Partial Nephrectomy
  • Robotic Prostatectomy
  • Robotic Surgery

About Dr. Gupta

Biography

Dr. Gupta received his B.S. (Biological Chemistry) from the University of Chicago in 1996. He received his M.D. from the University of Illinois at Chicago in 2002. He then performed his residency in urologic surgery at the University of Maryland Medical Center (2002-2008). He continued his training as a fellow in Urologic Oncology at the National Cancer Institute (NIH) in the Urologic Oncology Branch under the guidance of Dr. W. Marston Linehan (2008-2011). In 2011 he was recruited to the Department of Urology by Dr. Robert Flanigan as a fellowship trained urologic oncologist. Dr. Gupta holds a primary appointment in the Department of Urology, and has a joint appointment in the Department of Surgery and the Oncology Institute.

His primary clinical research interests pertain to bladder, kidney and prostate cancer. Dr. Gupta performs minimally invasive surgeries using the DaVinci Robotic Surgery platform. His clinical interests are to push the cutting edge of technology while optimizing cancer outcomes. He is also interested in the role of targeted therapies either before or after surgery to enhance cancer outcomes.

Dr. Gupta’s laboratory is located in the oncology institute. He has been named a Dean’s Office Clinical Scholar and splits his time between his clinical responsibilities and his research interests. His laboratory is active in creating pre-clinical models in bladder and kidney cancer to assess the effects of emerging targeted therapies.

Dr. Gupta has positioned Loyola to be a leader in robotic surgery and cutting edge urologic cancer surgery treatments. He has developed novel robotic approaches to kidney cancer surgery, prostate cancer and bladder cancer surgery. In addition, he has established the first MRI guided prostate fusion biopsy program in Illinois.

Dr. Gupta is an expert in urologic oncology and robotic surgery and lectures extensively on these subjects at the regional and national level. He in in the top 1% nationally for surgery volumes and his outcomes are excellent.

Interests
Golf, Camping, Family Time, Food & Wine, Photography, Tennis, Technology, Computers/technology

Medical Education

Medical School
University of Illinois College of Medicine, Chicago
Residency
University of Maryland at Baltimore - General Surgery
University of Maryland at Baltimore - Urology
Fellowship
  • National Cancer Institute (NCI) - Urologic Oncology

Board Certification

American Board of Urology

Research

  • Adhesive Bowel Obstruction Following Urologic Surgery: Improved Outcomes with Early Intervention. Blackwell, RH; Kothari, AN; Shah, A; Gang, W; Quek, ML; Luchette, FA; Flanigan, RC; Kuo, PC; Gupta, GN, Current urology
  • Complications of Recognized and Unrecognized Iatrogenic Ureteral Injury at Time of Hysterectomy: A Population Based Analysis Blackwell, R. H.; Kirshenbaum, E. J.; Shah, A. S.; Kuo, P. C.; Gupta, G. N.; Turk, T. M. T., The Journal of urology
  • Impact of Post-hospital Syndrome on Penile Prosthesis Outcomes: A Period of Global Health Risk. Kirshenbaum, EJ; Nelson, M; Hehemann, MC; Kothari, AN; Eguia, E; Farooq, A; Bresler, L; Gupta, G; Delos Santos, G, The Journal of urology
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  • Implications of postoperative pulmonary aspiration following major urologic surgery Kirshenbaum, E. J.; Blackwell, R. H.; Li, B.; Kothari, A. N.; Kuo, P. C.; Flanigan, R. C.; Gorbonos, A.; Gupta, G. N., The Canadian journal of urology
  • Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer (RAZOR): an open-label randomised, phase 3, non-inferiority trial., Parekh, DJ; Reis, IM; Castle, EP; Gonzalgo, ML; Woods, ME; Svatek, RS; Weizer, AZ; Konety, BR; Tollefson, M; Krupski, TL; Smith, ND; Shabsigh, A; Barocas, DA; Quek, ML; Dash, A; Kibel, AS; Shemanski, L; Pruthi, RS; Montgomery, JS; Weight, CJ; Sharp, DS; Chang, SS; Cookson, MS; Gupta, GN; Gorbonos, A; Uchio, EM; Skinner, E; Venkatramani, V; Soodana-Prakash, N; Kendrick, K; Smith, JA; Thompson, IM, Lancet (London, England)
  • The LACE Score as a Tool to Identify Radical Cystectomy Patients at Increased Risk of 90-Day Readmission and Mortality. Saluk, JL; Blackwell, RH; Gange, WS; Zapf, MAC; Kothari, AN; Kuo, PC; Quek, ML; Flanigan, RC; Gupta, GN, Current urology
  • Association Between Elements of Electronic Health Record Systems and the Weekend Effect in Urgent General Surgery Kothari, A. N.; Brownlee, S. A.; Blackwell, R. H.; Zapf, M. A.; Markossian, T.; Gupta, G. N.; Kuo, P. C., JAMA surgery
  • Design and Implementation of a Robotic Surgery Training Experience Logging System Baldea, K. G.; Thorwarth, R.; Bajic, P.; Quek, M. L.; Gupta, G. N., Journal of surgical education
  • Discordance between surgical care improvement project adherence and postoperative outcomes: implications for new Joint Commission standards Chang, V.; Blackwell, R. H.; Markossian, T.; Yau, R. M.; Blanco, B. A.; Zapf, M. A. C.; Abood, G. J.; Gupta, G. N.; Kuo, P. C.; Kothari, A. N., The Journal of surgical research
  • Functional Comparison of Renal Tumor Enucleation Versus Standard Partial Nephrectomy Dong, W.; Gupta, G. N.; Blackwell, R. H.; Wu, J.; Suk-Ouichai, C.; Shah, A.; Capodice, S. E.; Quek, M. L.; Caraballo Antonio, E.; Aguilar Palacios, D.; Remer, E. M.; Li, J.; Zabell, J.; Isharwal, S.; Campbell, S. C., European urology focus
  • Incidence of Adverse Contrast Reaction Following Nonintravenous Urinary Tract Imaging Blackwell, R. H.; Kirshenbaum, E. J.; Zapf, M. A. C.; Kothari, A. N.; Kuo, P. C.; Flanigan, R. C.; Gupta, G. N., European urology focus
  • Postoperative Urinary Retention is an Independent Predictor of Short- and Long-Term Future Bladder Outlet Procedure in Men Blackwell, R. H.; Vedachalam, S.; Shah, A. S.; Kothari, A. N.; Kuo, P. C.; Gupta, G. N.; Turk, T. M. T., The Journal of urology
  • Rates and Risk Factors for Opioid Dependence and Overdose After Urologic Surgery Shah, A. S.; Blackwell, R. H.; Kuo, P. C.; Gupta, G. N., The Journal of urology
  • Re: Csaba Berczi Ben Thomas, Zsolt Bacso, Tibor Flasko. Bilateral renal cancers: oncological and functional outcomes. Int Urol Nephrol 2016 (Epub ahead of print), Watson, M. J.; Sidana, A.; Singer, E. A.; Gupta, G. N.; Rastinehad, A. R.; Vourganti, S.; Bratslavsky, G.; Metwalli, A. R., International Urology and Nephrology
  • The Role of Cancer-Derived Exosomes in Tumorigenicity & Epithelial-to-Mesenchymal Transition Blackwell, R. H.; Foreman, K. E.; Gupta, G. N., Cancers
  • Tumor enucleation specimens of small renal tumors more frequently have a positive surgical margin than partial nephrectomy specimens but this is not associated with local tumor recurrence, Wang, L.; Hughes, I.; Snarskis, C.; Alvarez, H.; Feng, J.; Gupta, G. N.; Picken, M. M., Virchows Archiv : an international journal of pathology
  • Early Intervention during Acute Stone Admissions: Revealing "The Weekend Effect" in Urological Practice Blackwell, R. H.; Barton, G. J.; Kothari, A. N.; Zapf, M. A.; Flanigan, R. C.; Kuo, P. C.; Gupta, G. N., The Journal of urology
  • Epigallocatechin-3-Gallate Upregulates miR-221 to Inhibit Osteopontin-Dependent Hepatic Fibrosis Arffa, M. L.; Zapf, M. A.; Kothari, A. N.; Chang, V.; Gupta, G. N.; Ding, X.; Al-Gayyar, M. M.; Syn, W.; Elsherbiny, N. M.; Kuo, P. C.; Mi, Z., PLoS ONE
  • Functional Implications of Renal Tumor Enucleation Relative to Standard Partial Nephrectomy Blackwell, R. H.; Li, B.; Kozel, Z.; Zhang, Z.; Zhao, J.; Dong, W.; Capodice, S. E.; Barton, G.; Shah, A.; Wetterlin, J. J.; Quek, M. L.; Campbell, S. C.; Gupta, G. N., Urology
  • Impact of Post-Hospital Syndrome on Outcomes Following Elective Ambulatory Surgery, Brownlee, S. A.; Blackwell, R. H.; Blanco, B. A.; Zapf, M. A.; Kliethermes, S.; Gupta, G. N.; Kuo, P. C.; Kothari, A. N., Annals of Surgery
  • New onset postoperative atrial fibrillation predicts long-term cardiovascular events after gastrectomy Nassoiy, S. P.; Blackwell, R. H.; Kothari, A. N.; Besser, S.; Gupta, G. N.; Kuo, P. C.; Abood, G. J., American Journal of Surgery
  • Outcomes of percutaneous nephrolithotomy in spinal cord injury patients as compared to a matched cohort Baldea, K. G.; Blackwell, R. H.; Vedachalam, S.; Kothari, A. N.; Kuo, P. C.; Gupta, G. N.; Turk, T. M., Urolithiasis
  • PLK-1 Silencing in Bladder Cancer by siRNA Delivered With Exosomes Greco, K. A.; Franzen, C. A.; Foreman, K. E.; Flanigan, R. C.; Kuo, P. C.; Gupta, G. N., Urology
  • Standardized Reporting of Microscopic Renal Tumor Margins: Introduction of the Renal Tumor Capsule Invasion Scoring System Snarskis, C.; Calaway, A. C.; Wang, L.; Gondim, D.; Hughes, I.; Idrees, M.; Kliethermes, S.; Maniar, V.; Picken, M. M.; Boris, R. S.; Gupta, G. N., The Journal of urology
  • Tumor and Plasma Met Levels in Non-Metastatic Prostate Cancer. Kaye, DR; Pinto, PA; Cecchi, F; Reilly, J; Semerjian, A; Rabe, DC; Gupta, G; Choyke, PL; Bottaro, DP, PLoS ONE
  • Variable surgical outcomes after hospital consolidation: Implications for local health care delivery Chang, V.; Blackwell, R. H.; Yau, R. M.; Besser, S.; Albright, J. M.; Gupta, G. N.; Kuo, P. C.; Kothari, A. N., Surgery
  • Alcohol inhibits osteopontin-dependent transforming growth factor-beta1 expression in human mesenchymal stem cells Driver, J.; Weber, C. E.; Callaci, J. J.; Kothari, A. N.; Zapf, M. A.; Roper, P. M.; Borys, D.; Franzen, C. A.; Gupta, G. N.; Wai, P. Y.; Zhang, J.; Denning, M. F.; Kuo, P. C.; Mi, Z., The Journal of biological chemistry
  • Components of Hospital Perioperative Infrastructure Can Overcome the Weekend Effect in Urgent General Surgery Procedures Kothari, A. N.; Zapf, M. A.; Blackwell, R. H.; Markossian, T.; Chang, V.; Mi, Z.; Gupta, G. N.; Kuo, P. C., Annals of Surgery
  • Critical histologic appraisal of the pseudocapsule of small renal tumors Wang, L.; Feng, J.; Alvarez, H.; Snarskis, C.; Gupta, G.; Picken, M. M., Virchows Archiv : an international journal of pathology
  • Editorial comment Ellimoottil, C.; Gupta, G. N.; Quek, M. L., Urology
  • Gleason 6 Prostate Cancer: Translating Biology into Population Health. Eggener, SE; Badani, K; Barocas, DA; Barrisford, GW; Cheng, JS; Chin, AI; Corcoran, A; Epstein, JI; George, AK; Gupta, GN; Hayn, MH; Kauffman, EC; Lane, B; Liss, MA; Mirza, M; Morgan, TM; Moses, K; Nepple, KG; Preston, MA; Rais-Bahrami, S; Resnick, MJ; Siddiqui, MM; Silberstein, J; Singer, EA; Sonn, GA; Sprenkle, P; Stratton, KL; Taylor, J; Tomaszewski, J; Tollefson, M; Vickers, A; White, WM; Lowrance, WT, The Journal of urology
  • Green tea component epigallocatechin-3-gallate decreases expression of osteopontin via a decrease in mRNA half-life in cell lines of metastatic hepatocellular carcinoma Zapf, M. A.; Kothari, A. N.; Weber, C. E.; Arffa, M. L.; Wai, P. Y.; Driver, J.; Gupta, G. N.; Kuo, P. C.; Mi, Z., Surgery
  • New Onset Postoperative Atrial Fibrillation Predicts Long-Term Cardiovascular Events Following Radical Cystectomy Blackwell, R. H.; Ellimoottil, C.; Bajic, P.; Kothari, A.; Zapf, M.; Kliethermes, S.; Flanigan, R. C.; Quek, M. L.; Kuo, P. C.; Gupta, G. N., The Journal of urology
  • Open Versus Robotic Radical Prostatectomy in Obese Men Ellimoottil, C.; Roghmann, F.; Blackwell, R.; Kadlec, A.; Greco, K.; Quek, M. L.; Sun, M.; Trinh, Q. D.; Gupta, G., Current urology
  • Positive surgical margins in renal cell carcinoma: translating tumor biology into clinical outcomes Picken, M. M.; Wang, L.; Gupta, G. N., American Journal of Clinical Pathology
  • Re: Raj Satkunasivam Sheaumei Tsai, Sumeet Syan, et al. Robotic Unclamped "Minimal-margin" Partial Nephrectomy: Ongoing Refinement of the Anatomic Zero-ischemia Concept. Eur Urol. In press. http://dx.doi.org.archer.luhs.org/10.1016/j.eururo.2015.04.044, Campbell, S. C.; Gupta, G. N.; Uzzo, R. G.; Kutikov, A., European urology
  • Robot-assisted renal tumor enucleo-resection in patients with a solitary kidney. Calaway, AC; Gupta, GN; Bhandar, A; Eun, D; Boris, RS, The Canadian journal of urology
  • The "weekend effect" in urgent general operative procedures Zapf, M. A.; Kothari, A. N.; Markossian, T.; Gupta, G. N.; Blackwell, R. H.; Wai, P. Y.; Weber, C. E.; Driver, J.; Kuo, P. C., Surgery
  • Three-Dimensional Renal Parenchymal Volume as a Surrogate for Renal Function Estimation in Obstructed Kidneys Undergoing Surgical Repair Martinez-Suarez, H. J.; Durso, T.; Kadlec, A. O.; Gupta, G. N.; Farooq, A. V.; Turk, T., Journal of endourology / Endourological Society
  • Tumor Enucleation for Sporadic Localized Kidney Cancer: Pro and Con Gupta, G. N.; Boris, R. S.; Campbell, S. C.; Zhang, Z., The Journal of urology
  • Urinary Exosomes: The Potential for Biomarker Utility Intercellular Signaling and Therapeutics in Urological Malignancy, Franzen, C. A.; Blackwell, R. H.; Foreman, K. E.; Kuo, P. C.; Flanigan, R. C.; Gupta, G. N., The Journal of urology
  • Urothelial cells undergo epithelial-to-mesenchymal transition after exposure to muscle invasive bladder cancer exosomes Franzen, C. A.; Blackwell, R. H.; Todorovic, V.; Greco, K. A.; Foreman, K. E.; Flanigan, R. C.; Kuo, P. C.; Gupta, G. N., Oncogenesis
  • 3-dimensional reconstruction volume (3DV): a novel method for volume measurement in kidney cancer Durso, T.; Carnell, J.; Turk, T.; Gupta, G. N., Journal of endourology / Endourological Society
  • Characterization of uptake and internalization of exosomes by bladder cancer cells Franzen, C. A.; Simms, P. E.; Van Huis, A. F.; Foreman, K. E.; Kuo, P. C.; Gupta, G. N., BioMed research international
  • Emetine dihydrochloride: a novel therapy for bladder cancer Foreman, K. E.; Jesse, J. N., 3rd; Kuo, P. C.; Gupta, G. N., The Journal of urology
  • Expanding the morphologic spectrum of adult biphasic renal tumors--mixed epithelial and stromal tumor of the kidney with focal papillary renal cell carcinoma: case report and review of the literature Mudaliar, K. M.; Mehta, V.; Gupta, G. N.; Picken, M. M., International Journal of Surgical Pathology
  • Osteopontin mediates an MZF1-TGF-beta1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer Weber, C. E.; Kothari, A. N.; Wai, P. Y.; Li, N. Y.; Driver, J.; Zapf, M. A.; Franzen, C. A.; Gupta, G. N.; Osipo, C.; Zlobin, A.; Syn, W. K.; Zhang, J.; Kuo, P. C.; Mi, Z., Oncogene
  • Perioperative functional, and oncologic outcomes of partial adrenalectomy for multiple ipsilateral pheochromocytomas, Gupta, G. N.; Benson, J. S.; Ross, M. J.; Sundaram, V. S.; Lin, K. Y.; Pinto, P. A.; Linehan, W. M.; Bratslavsky, G., Journal of endourology / Endourological Society
  • Renal paraganglioma: report of a case managed by robotic assisted laparoscopic partial nephrectomy and review of the literature Bahar, B.; Pambuccian, S. E.; Gupta, G. N.; Barkan, G. A., Case reports in urology
  • Three-dimensional reconstruction volume: a novel method for volume measurement in kidney cancer Durso, T. A.; Carnell, J.; Turk, T. T.; Gupta, G. N., Journal of endourology / Endourological Society
  • Adrenal nodular hyperplasia in hereditary leiomyomatosis and renal cell cancer Shuch, B.; Ricketts, C. J.; Vocke, C. D.; Valera, V. A.; Chen, C. C.; Gautam, R.; Gupta, G. N.; Gomez Macias, G. S.; Merino, M. J.; Bratslavsky, G.; Linehan, W. M., The Journal of urology
  • Evolving therapeutic targets in renal cell carcinoma Singer, E. A.; Gupta, G. N.; Marchalik, D.; Srinivasan, R., Current opinion in oncology
  • Feasibility and outcomes of laparoscopic renal intervention after prior open ipsilateral retroperitoneal surgery Boris, R. S.; Gupta, G. N.; Benson, J. S.; Linehan, W. M.; Pinto, P. A.; Bratslavsky, G., Journal of endourology / Endourological Society
  • Robot-assisted laparoscopic partial nephrectomy for tumors greater than 4 cm and high nephrometry score: feasibility renal functional, and oncological outcomes with minimum 1 year follow-up, Gupta, G. N.; Boris, R.; Chung, P.; Linehan, W. M.; Pinto, P. A.; Bratslavsky, G., Urologic oncology
  • Low suspicion lesions on multiparametric magnetic resonance imaging predict for the absence of high-risk prostate cancer Yerram, N. K.; Volkin, D.; Turkbey, B.; Nix, J.; Hoang, A. N.; Vourganti, S.; Gupta, G. N.; Linehan, W. M.; Choyke, P. L.; Wood, B. J.; Pinto, P. A., BJU international
  • Multiparametric magnetic resonance imaging and ultrasound fusion biopsy detect prostate cancer in patients with prior negative transrectal ultrasound biopsies Vourganti, S.; Rastinehad, A.; Yerram, N. K.; Nix, J.; Volkin, D.; Hoang, A.; Turkbey, B.; Gupta, G. N.; Kruecker, J.; Linehan, W. M.; Choyke, P. L.; Wood, B. J.; Pinto, P. A., The Journal of urology
  • Need for nucleic Acid testing in countries with high prevalence of transfusion-transmitted infections Jain, R.; Aggarwal, P.; Gupta, G. N., ISRN hematology
  • Outcomes of patients with surgically treated bilateral renal masses and a minimum of 10 years of followup Singer, E. A.; Vourganti, S.; Lin, K. Y.; Gupta, G. N.; Pinto, P. A.; Rastinehad, A. R.; Linehan, W. M.; Bratslavsky, G., The Journal of urology
  • Partial adrenalectomy minimizes the need for long-term hormone replacement in pediatric patients with pheochromocytoma and von Hippel-Lindau syndrome Volkin, D.; Yerram, N.; Ahmed, F.; Lankford, D.; Baccala, A.; Gupta, G. N.; Hoang, A.; Nix, J.; Metwalli, A. R.; Lang, D. M.; Bratslavsky, G.; Linehan, W. M.; Pinto, P. A., Journal of pediatric surgery
  • Targeted therapeutic strategies for the management of renal cell carcinoma Singer, E. A.; Gupta, G. N.; Srinivasan, R., Current opinion in oncology
  • Costs and benefits of generic prescribing after a kidney transplant Gupta, Gaurav; Batra, R.; Alachkar, Nada, Practice Nursing
  • Robot-assisted laparoscopic partial adrenalectomy for pheochromocytoma: the National Cancer Institute technique Asher, K. P.; Gupta, G. N.; Boris, R. S.; Pinto, P. A.; Linehan, W. M.; Bratslavsky, G., European urology
  • Update on targeted therapies for clear cell renal cell carcinoma Singer, E. A.; Gupta, G. N.; Srinivasan, R., Current opinion in oncology
  • Oncological outcomes of partial nephrectomy for multifocal renal cell carcinoma greater than 4 cm Gupta, G. N.; Peterson, J.; Thakore, K. N.; Pinto, P. A.; Linehan, W. M.; Bratslavsky, G., The Journal of urology
  • Bladder urothelial cells from patients with interstitial cystitis have an increased sensitivity to carbachol Gupta, G. N.; Lu, S. G.; Gold, M. S.; Chai, T. C., Neurourology and Urodynamics
  • Protein-coated microcrystals of Pseudomonas aeruginosa PseA lipase Gaur, R.; Gupta, G. N.; Vamsikrishnan, M.; Khare, S. K., Applied Biochemistry and Biotechnology