David J. Wilber, MD, FAHA, FACC


Pediatrics, Pediatric Cardiology
Co-Director, Cardiovascular Research Institute, Director, Cardiovascular Institute, Medical Director, Clinical Electrophysiology

Languages Spoken

English, French

Clinical Expertise

  • Ablation Of Atrial Fibrillation, Alternatives To Anticoagulation For AF, Heart Failure
  • Arrhythmias, Electrophysiology, Ablation Catheter Applications For Complex Arrhythmias

About Dr. Wilber


Medical Education

Medical School
Northwestern University Feinberg School of Medicine
Northwestern University McGaw Medical Center - Internal Medicine: General
University of Michigan Medical Center - Cardiology, Massachusetts General Hospital - Clinical Cardiac Electrophysiology

Board Certification

American Board of Internal Medicine Subspecialty Clinical Cardiac Electrophysiology
Cardiovascular Disease
American Board of Internal Medicine Subspecialty


  • Multicenter Automatic Defibrillator Implantation Trial-Subcutaneous Implantable Cardioverter Defibrillator (MADIT S-ICD): Design and clinical protocol Kutyifa, V.; Beck, C.; Brown, M. W.; Cannom, D.; Daubert, J.; Estes, M.; Greenberg, H.; Goldenberg, I.; Hammes, S.; Huang, D.; Klein, H.; Knops, R.; Kosiborod, M.; Poole, J.; Schuger, C.; Singh, J. P.; Solomon, S.; Wilber, D.; Zareba, W.; Moss, A. J.; MADIT S-ICD Executive Committee, American Heart Journal
  • TEMPORARY REMOVAL: 2017 HRS/EHRA/ECAS/APHRS/SOLAECE Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation Calkins, H.; Hindricks, G.; Cappato, R.; Kim, Y. H.; Saad, E. B.; Aguinaga, L.; Akar, J. G.; Badhwar, V.; Brugada, J.; Camm, J.; Chen, P. S.; Chen, S. A.; Chung, M. K.; Nielsen, J. C.; Curtis, A. B.; Davies, D. W.; Day, J. D.; d'Avila, A.; Natasja de Groot, N. M. S.; Di Biase, L.; Duytschaever, M.; Edgerton, J. R.; Ellenbogen, K. A.; Ellinor, P. T.; Ernst, S.; Fenelon, G.; Gerstenfeld, E. P.; Haines, D. E.; Haissaguerre, M.; Helm, R. H.; Hylek, E.; Jackman, W. M.; Jalife, J.; Kalman, J. M.; Kautzner, J.; Kottkamp, H.; Kuck, K. H.; Kumagai, K.; Lee, R.; Lewalter, T.; Lindsay, B. D.; Macle, L.; Mansour, M.; Marchlinski, F. E.; Michaud, G. F.; Nakagawa, H.; Natale, A.; Nattel, S.; Okumura, K.; Packer, D.; Pokushalov, E.; Reynolds, M. R.; Sanders, P.; Scanavacca, M.; Schilling, R.; Tondo, C.; Tsao, H. M.; Verma, A.; Wilber, D. J.; Yamane, T., Heart Rhythm
  • Conversion of persistent atrial fibrillation to sinus rhythm after LAA ligation with the LARIAT device Badhwar, N.; Mittal, S.; Rasekh, A.; Vasaiwala, S.; Musat, D.; S Naeini, P.; Fang, Q.; Nentwich, K.; Deneke, T.; Chang, J.; Lakkireddy, D.; Wilber, D.; Lee, R. J., INTERNATIONAL JOURNAL OF CARDIOLOGY
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  • The Occurrence of Implantable Cardioverter Defibrillator Therapies After Generator Replacement in Patients Who No Longer Meet Primary Prevention Indications Kawata, H.; Hirai, T.; Doukas, D.; Hirai, R.; Steinbrunner, J.; Wilson, J.; Noda, T.; Hsu, J.; Krummen, D.; Feld, G.; Wilber, D.; Santucci, P.; Birgersdotter-Green, U., Journal of cardiovascular electrophysiology
  • Comparison of primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction during and prior to availability of an in-house STEMI system: early experience and intermediate outcomes of the HARRT program for achieving routine D2B times <60 minutes Nguyen, B.; Fennessy, M.; Leya, F.; Nowak, W.; Ryan, M.; Freeberg, S.; Gill, J.; Dieter, R. S.; Steen, L.; Lewis, B.; Cichon, M.; Probst, B.; Jarotkiewicz, M.; Wilber, D.; Lopez, J. J., Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
  • Left atrial volume assessment in atrial fibrillation using multimodality imaging: a comparison of echocardiography invasive three-dimensional CARTO and cardiac magnetic resonance imaging, Rabbat, M. G.; Wilber, D.; Thomas, K.; Malick, O.; Bashir, A.; Agrawal, A.; Biswas, S.; Sanagala, T.; Syed, M. A., The international journal of cardiovascular imaging
  • Lesion Size and Safety Comparison between the Novel Flex Tip on the FlexAbility Ablation Catheter and the Solid Tips on the ThermoCool and ThermoCool SF Ablation Catheters Winterfield, J. R.; Jensen, J.; Gilbert, T.; Marchlinski, F.; Natale, A.; Packer, D.; Reddy, V.; Mahapatra, S.; Wilber, D. J., Journal of cardiovascular electrophysiology
  • Long-Term Mortality After Ablation of Ischemic Ventricular Tachycardia: Not Inducible Is Not Enough Wilber, D. J., Journal of the American College of Cardiology
  • Percutaneous alternative to the Maze procedure for the treatment of persistent or long-standing persistent atrial fibrillation (aMAZE trial): Rationale and design Lee, R. J.; Lakkireddy, D.; Mittal, S.; Ellis, C.; Connor, J. T.; Saville, B. R.; Wilber, D., American Heart Journal
  • The Lariat for Left Atrial Appendage Closure: Rehash of Known Literature or a True Analysis? Nagaraj, H.; Wilber, D.; Lakkireddy, D. R., JAMA internal medicine
  • Uninterrupted rivaroxaban vs. uninterrupted vitamin K antagonists for catheter ablation in non-valvular atrial fibrillation Cappato, R.; Marchlinski, F. E.; Hohnloser, S. H.; Naccarelli, G. V.; Xiang, J.; Wilber, D. J.; Ma, C. S.; Hess, S.; Wells, D. S.; Juang, G.; Vijgen, J.; Hugl, B. J.; Balasubramaniam, R.; De Chillou, C.; Davies, D. W.; Fields, L. E.; Natale, A.; VENTURE-AF Investigators, EUROPEAN HEART JOURNAL
  • Ablation of the epicardial substrate in ventricular tachycardia associated with structural heart disease: outside in or inside out? Wilber, D. J., Journal of the American College of Cardiology
  • Association of atrial tissue fibrosis identified by delayed enhancement MRI and atrial fibrillation catheter ablation: the DECAAF study Marrouche, N. F.; Wilber, D.; Hindricks, G.; Jais, P.; Akoum, N.; Marchlinski, F.; Kholmovski, E.; Burgon, N.; Hu, N.; Mont, L.; Deneke, T.; Duytschaever, M.; Neumann, T.; Mansour, M.; Mahnkopf, C.; Herweg, B.; Daoud, E.; Wissner, E.; Bansmann, P.; Brachmann, J., JAMA : the journal of the American Medical Association
  • Mortality reduction in relation to implantable cardioverter defibrillator programming in the Multicenter Automatic Defibrillator Implantation Trial-Reduce Inappropriate Therapy (MADIT-RIT) Ruwald, A. C.; Schuger, C.; Moss, A. J.; Kutyifa, V.; Olshansky, B.; Greenberg, H.; Cannom, D. S.; Estes, N. A.; Ruwald, M. H.; Huang, D. T.; Klein, H.; McNitt, S.; Beck, C. A.; Goldstein, R.; Brown, M. W.; Kautzner, J.; Shoda, M.; Wilber, D.; Zareba, W.; Daubert, J. P., Circulation.Arrhythmia and electrophysiology
  • Paroxysmal AF Catheter Ablation With a Contact Force Sensing Catheter: Results of the Prospective Multicenter SMART-AF Trial, Natale, A.; Reddy, V. Y.; Monir, G.; Wilber, D. J.; Lindsay, B. D.; McElderry, H. T.; Kantipudi, C.; Mansour, M. C.; Melby, D. P.; Packer, D. L.; Nakagawa, H.; Zhang, B.; Stagg, R. B.; Boo, L. M.; Marchlinski, F. E., Journal of the American College of Cardiology
  • Survival with cardiac-resynchronization therapy in mild heart failure Goldenberg, I.; Kutyifa, V.; Klein, H. U.; Cannom, D. S.; Brown, M. W.; Dan, A.; Daubert, J. P.; Estes, N. A., 3rd; Foster, E.; Greenberg, H.; Kautzner, J.; Klempfner, R.; Kuniss, M.; Merkely, B.; Pfeffer, M. A.; Quesada, A.; Viskin, S.; McNitt, S.; Polonsky, B.; Ghanem, A.; Solomon, S. D.; Wilber, D.; Zareba, W.; Moss, A. J., The New England journal of medicine
  • Usefulness of left ventricular diastolic function to predict recurrence of atrial fibrillation in patients with preserved left ventricular systolic function Hirai, T.; Cotseones, G.; Makki, N.; Agrawal, A.; Wilber, D. J.; Barron, J. T., The American Journal of Cardiology
  • Catheter ablation of ventricular arrhythmias: targets tactics, and tools, Winterfield, J. R.; Mahapatra, S.; Wilber, D. J., CURRENT OPINION IN CARDIOLOGY
  • Comparison of two methods of right atrial volume assessment using cardiac magnetic resonance imaging: area-length method versus multislice volumetric method Biswas, S.; Sanagala, T.; Wilber, D.; Syed, M. A., Journal of Cardiovascular Magnetic Resonance (BioMed Central)
  • Left atrial volume assessment by area-length method compared to multislice volumetric method using cardiovascular magnetic resonance imaging Bashir, A.; Rabbat, M.; Biswas, S.; Wilber, D.; Sanagala, T.; Syed, M. A., Journal of Cardiovascular Magnetic Resonance (BioMed Central)
  • Fibroblasts focal triggers, and persistent atrial fibrillation: is there a connection?, Wilber, D. J., Circulation: Arrhythmia & Electrophysiology
  • Safety of the Open-Irrigated Ablation Catheter for Radiofrequency Ablation: Safety Analysis from Six Clinical Studies Waldo, A. L.; Wilber, D. J.; Marchlinski, F. E.; Stevenson, W. G.; Aker, B.; Boo, L. M.; Jackman, W. M., Pacing & Clinical Electrophysiology
  • Venice Chart International Consensus Document on Atrial Fibrillation Ablation: 2011 Update Raviele, A.; Natale, A.; Calkins, H.; Camm, J. A.; Cappato, R.; Ann Chen, S.; Connolly, S. J.; Damiano Jr, R.; De Ponti, R.; Edgerton, J. R.; Haissaguerre, M.; Hindricks, G.; Ho, S. Y.; Jalife, J.; Kirchhof, P.; Kottkamp, H.; Kuck, K. H.; Marchlinski, F. E.; Packer, D. L.; Pappone, C.; Prystowsky, E.; Reddy, V. K.; Themistoclakis, S.; Verma, A.; Wilber, D. J.; Willems, S., Journal of cardiovascular electrophysiology
  • Altered desmosomal proteins in granulomatous myocarditis and potential pathogenic links to arrhythmogenic right ventricular cardiomyopathy Asimaki, A.; Tandri, H.; Duffy, E. R.; Winterfield, J. R.; Mackey-Bojack, S.; Picken, M. M.; Cooper, L. T.; Wilber, D. J.; Marcus, F. I.; Basso, C.; Thiene, G.; Tsatsopoulou, A.; Protonotarios, N.; Stevenson, W. G.; McKenna, W. J.; Gautam, S.; Remick, D. G.; Calkins, H.; Saffitz, J. E., Circulation.Arrhythmia and electrophysiology
  • Selective CFAE Targeting for Atrial Fibrillation Study (SELECT AF): Clinical Rationale Design, and Implementation, Verma, A.; Sanders, P.; Macle, L.; Champagne, J.; Nair, G. M.; Calkins, H.; Wilber, D. J., Journal of cardiovascular electrophysiology
  • Comparison of antiarrhythmic drug therapy and radiofrequency catheter ablation in patients with paroxysmal atrial fibrillation: a randomized controlled trial. Wilber, D. J.; Pappone, C.; Neuzil, P.; De Paola, A.; Marchlinski, F.; Natale, A.; Macle, L.; Daoud, E. G.; Calkins, H.; Hall, B.; Reddy, V.; Augello, G.; Reynolds, M. R.; Vinekar, C.; Liu, C. Y.; Berry, S. M.; Berry, D. A., JAMA
  • DeCFAEnating atrial fibrillation: narrowing the targets... complex and/or fractionated atrial electrogram Wilber, D. J., Journal of cardiovascular electrophysiology
  • Pericardial fat is independently associated with human atrial fibrillation. Al Chekakie, M. O.; Welles, C. C.; Metoyer, R.; Ibrahim, A.; Shapira, A. R.; Cytron, J.; Santucci, P.; Wilber, D. J.; Akar, J. G., Journal of the American College of Cardiology
  • Electroanatomic mapping of postpacing intervals clarifies the complete active circuit and variants in atrial flutter. Santucci, P. A.; Varma, N.; Cytron, J.; Akar, J. G.; Wilber, D. J.; Al Chekakie, M. O.; Brysiewicz, N., Heart Rhythm
  • Electrophysiologic Testing for Risk Stratification Following Myocardial Infarction: Dead or Alive? WILBER, D. J., Journal of cardiovascular electrophysiology
  • Prospective study of cardiac sarcoid mimicking arrhythmogenic right ventricular dysplasia Vasaiwala, S. C.; Finn, C.; Delpriore, J.; Leya, F.; Gagermeier, J.; Akar, J. G.; Santucci, P.; Dajani, K.; Bova, D.; Picken, M. M.; Basso, C.; Marcus, F.; Wilber, D. J., Journal of cardiovascular electrophysiology
  • Acute onset human atrial fibrillation is associated with local cardiac platelet activation and endothelial dysfunction. Akar, J. G.; Jeske, W.; Wilber, D. J., Journal of the American College of Cardiology
  • Endothelial dysfunction in heart failure identifies responders to cardiac resynchronization therapy. Akar, J. G.; Al Chekakie, M. O.; Fugate, T.; Moran, L.; Froloshki, B.; Varma, N.; Santucci, P.; Wilber, D. J.; Matsumura, M. E., Heart Rhythm
  • Newly diagnosed arrhythmogenic right ventricular dysplasia in an octogenarian. Akar, J. G.; Singh, M.; Auseon, A. J.; Wilber, D. J., Journal of cardiovascular electrophysiology
  • No benefit from defibrillation threshold testing in the SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial). Blatt, J. A.; Poole, J. E.; Johnson, G. W.; Callans, D. J.; Raitt, M. H.; Reddy, R. K.; Marchlinski, F. E.; Yee, R.; Guarnieri, T.; Talajic, M.; Wilber, D. J.; Anderson, J.; Chung, K.; Wong, W. S.; Mark, D. B.; Lee, K. L.; Bardy, G. H., Journal of the American College of Cardiology
  • Prognostic importance of defibrillator shocks in patients with heart failure. Poole, J. E.; Johnson, G. W.; Hellkamp, A. S.; Anderson, J.; Callans, D. J.; Raitt, M. H.; Reddy, R. K.; Marchlinski, F. E.; Yee, R.; Guarnieri, T.; Talajic, M.; Wilber, D. J.; Fishbein, D. P.; Packer, D. L.; Mark, D. B.; Lee, K. L.; Bardy, G. H., New England Journal of Medicine
  • Prospective study of atrial fibrillation termination during ablation guided by automated detection of fractionated electrograms. Porter, M.; Spear, W.; Akar, J. G.; Helms, R.; Brysiewicz, N.; Santucci, P.; Wilber, D. J., Journal of cardiovascular electrophysiology
  • Ethanol septal ablation for refractory ventricular tachycardia Ramana, R. K.; Wilber, D. J.; Leya, F., Journal of Invasive Cardiology
  • Surface electrocardiographic patterns and electrophysiologic characteristics of atrial flutter following modified radiofrequency MAZE procedures Akar, J. G.; Al Chekakie, M. O.; Hai, A.; Brysiewicz, N.; Porter, M.; Varma, N.; Santucci, P.; Wilber, D. J., Journal of cardiovascular electrophysiology
  • The effects of statins and renin-angiotensin system blockers on atrial fibrillation recurrence following antral pulmonary vein isolation Al Chekakie, M. O.; Akar, J. G.; Wang, F.; Al Muradi, H.; Wu, J.; Santucci, P.; Varma, N.; Wilber, D. J., Journal of cardiovascular electrophysiology
  • Idiopathic epicardial left ventricular tachycardia originating remote from the sinus of Valsalva: electrophysiological characteristics catheter ablation, and identification from the 12-lead electrocardiogram., Daniels, D. V.; Lu, Y. Y.; Morton, J. B.; Santucci, P. A.; Akar, J. G.; Green, A.; Wilber, D. J., Circulation
  • Substrate-based endocardial ablation of postinfarction ventricular tachycardia Oza, S.; Wilber, D. J., Heart Rhythm
  • Ablation of idiopathic right ventricular outflow tract tachycardia: current perspectives Joshi, S.; Wilber, D. J., Journal of cardiovascular electrophysiology
  • Spatial resolution of pacemapping and activation mapping in patients with idiopathic right ventricular outflow tract tachycardia. Azegami, K.; Wilber, D. J.; Arruda, M.; Lin, A. C.; Denman, R. A., Journal of cardiovascular electrophysiology
  • Electroanatomic mapping of the right ventricle in a patient with a giant epsilon wave ventricular tachycardia, and cardiac sarcoidosis., Santucci, P. A.; Morton, J. B.; Picken, M. M.; Wilber, D. J., Journal of cardiovascular electrophysiology
  • Influence of age and gender on the mechanism of supraventricular tachycardia Porter, M. J.; Morton, J. B.; Denman, R.; Lin, A. C.; Tierney, S.; Santucci, P. A.; Cai, J. J.; Madsen, N.; Wilber, D. J., Heart Rhythm