CONTACT INFORMATION http://www.loyola.org
Xun Ai
M.D.
  • Assistant Professor
  • Cell and Molecular Physiology
Research Keywords
  • Arrhythmias
Publications

Bacterial protein AvrA stabilizes intestinal epithelial tight junctions via blockage of the C-Jun N-terminal kinase pathwayZhang,Y.; Wu,S.; Ma,J.; Xia,Y.; Ai,X.; Sun,J.Tissue barriers 2015 ;3(1-2):e972849

Voltage and Calcium Dual Channel Optical Mapping of Cultured HL-1 Atrial Myocyte MonolayerYan,J.; Thomson,J. K.; Zhao,W.; Fast,V. G.; Ye,T.; Ai,X.Journal of visualized experiments : JoVE 2015 ;(97). doi(97):10.3791/52542

Genetic deletion of Rnd3/RhoE results in mouse heart calcium leakage through upregulation of protein kinase A signalingYang,X.; Wang,T.; Lin,X.; Yue,X.; Wang,Q.; Wang,G.; Fu,Q.; Ai,X.; Chiang,D. Y.; Miyake,C. Y.; Wehrens,X. H.; Chang,J.Circulation research 2015 ;116(1):e1-e10

SR calcium handling dysfunction, stress-response signaling pathways, and atrial fibrillationAi,X.Frontiers in physiology 2015 ;6( ):46

Heart failureWang,Y.; Yang,Y.; Ai,X.Thescientificworldjournal 2014 ;2014( ):730651

Connexin40 abnormalities and atrial fibrillation in the human heartGemel,J.; Levy,A. E.; Simon,A. R.; Bennett,K. B.; Ai,X.; Akhter,S.; Beyer,E. C.Journal of Molecular and Cellular Cardiology 2014 ;76C( ):159-168

Novel methods of automated quantification of gap junction distribution and interstitial collagen quantity from animal and human atrial tissue sectionsYan,J.; Thomson,J. K.; Wu,X.; Zhao,W.; Pollard,A. E.; Ai,X.PLoS ONE 2014 ;9(8):e104357

c-Jun N-terminal kinase activation contributes to reduced connexin43 and development of atrial arrhythmiasYan,J.; Kong,W.; Zhang,Q.; Beyer,E. C.; Walcott,G.; Fast,V. G.; Ai,X.Cardiovascular research 2013 ;97(3):589-597

Sex differences in repolarization and slow delayed rectifier potassium current and their regulation by sympathetic stimulation in rabbitsZhu,Y.; Ai,X.; Oster,R. A.; Bers,D. M.; Pogwizd,S. M.Pflugers Archiv : European journal of physiology 2013 ;465(6):805-818

Role of RyR2 phosphorylation at S2814 during heart failure progressionRespress,J. L.; van Oort,R. J.; Li,N.; Rolim,N.; Dixit,S. S.; deAlmeida,A.; Voigt,N.; Lawrence,W. S.; Skapura,D. G.; Skardal,K.; Wisloff,U.; Wieland,T.; Ai,X.; Pogwizd,S. M.; Dobrev,D.; Wehrens,X. H.Circulation research 2012 ;110(11):1474-1483

Enhanced activation of p21-activated kinase 1 in heart failure contributes to dephosphorylation of connexin 43Ai,X.; Jiang,A.; Ke,Y.; Solaro,R. J.; Pogwizd,S. M.Cardiovascular research 2011 ;92(1):106-114

Connexin43 knockdown or overexpression modulates cell coupling in control and failing rabbit left ventricular myocytesAi,X.; Zhao,W.; Pogwizd,S. M.Cardiovascular research 2010 ;85(4):751-762

Arrhythmogenic effects of beta2-adrenergic stimulation in the failing heart are attributable to enhanced sarcoplasmic reticulum Ca loadDesantiago,J.; Ai,X.; Islam,M.; Acuna,G.; Ziolo,M. T.; Bers,D. M.; Pogwizd,S. M.Circulation research 2008 ;102(11):1389-1397

Decreased intercellular coupling improves the function of cardiac pacemakers derived from mouse embryonic stem cellsFahrenbach,J. P.; Ai,X.; Banach,K.Journal of Molecular and Cellular Cardiology 2008 ;45(5):642-649

Intra-sarcoplasmic reticulum free [Ca2+] and buffering in arrhythmogenic failing rabbit heart.Guo,T.; Ai,X.; Shannon,T. R.; Pogwizd,S. M.; Bers,D. M.Circulation research 2007 ;101(8):802-810

Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failureAi,X.; Curran,J. W.; Shannon,T. R.; Bers,D. M.; Pogwizd,S. M.Circulation research 2005 ;97(12):1314-1322

Connexin 43 downregulation and dephosphorylation in nonischemic heart failure is associated with enhanced colocalized protein phosphatase type 2AAi,X.; Pogwizd,S. M.Circulation research 2005 ;96(1):54-63

Expression and phosphorylation of the na-pump regulatory subunit phospholemman in heart failureBossuyt,J.; Ai,X.; Moorman,J. R.; Pogwizd,S. M.; Bers,D. M.Circulation research 2005 ;97(6):558-565

Ultrastructural analysis of peripheral-nerve regeneration within a nerve conduitLi,J.; Yan,J. G.; Ai,X.; Hu,S.; Gu,Y. D.; Matloub,H. S.; Sanger,J. R.JOURNAL OF RECONSTRUCTIVE MICROSURGERY 2004 ;20(7):565-569

Education
Medical School
  • Suzhou University School of Medicine
Residency
  • Suzhou Second People's Hospital, Obstetrics & Gynecology
Languages
  • Chinese