Wei Qiu
  • Assistant Professor
  • Surgical Research
Research Keywords
  • Liver Functions

FAK is required for c-Met/beta-catenin-driven hepatocarcinogenesisShang,N.; Arteaga,M.; Zaidi,A.; Stauffer,J.; Cotler,S. J.; Zeleznik-Le,N. J.; Zhang,J.; Qiu,W.Hepatology (Baltimore, Md.) 2015 ;61(1):214-226

BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal antiinflammatory drugsLeibowitz,B.; Qiu,W.; Buchanan,M. E.; Zou,F.; Vernon,P.; Moyer,M. P.; Yin,X. M.; Schoen,R. E.; Yu,J.; Zhang,L.Proceedings of the National Academy of Sciences of the United States of America 2014 ;111(46):16520-16525

ADAR1 is essential for intestinal homeostasis and stem cell maintenanceQiu,W.; Wang,X.; Buchanan,M.; He,K.; Sharma,R.; Zhang,L.; Wang,Q.; Yu,J.Cell death & disease 2013 ;4( ):e599

An apoptosis-independent role of SMAC in tumor suppressionQiu,W.; Liu,H.; Sebastini,A.; Sun,Q.; Wang,H.; Zhang,L.; Yu,J.Oncogene 2013 ;32(19):2380-2389

Investigation of nuclear nano-morphology marker as a biomarker for cancer risk assessment using a mouse modelBista,R. K.; Uttam,S.; Hartman,D. J.; Qiu,W.; Yu,J.; Zhang,L.; Brand,R. E.; Liu,Y.Journal of Biomedical Optics 2012 ;17(6):066014

PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and miceQiu,W.; Wu,B.; Wang,X.; Buchanan,M. E.; Regueiro,M. D.; Hartman,D. J.; Schoen,R. E.; Yu,J.; Zhang,L.The Journal of clinical investigation 2011 ;121(5):1722-1732

PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in miceQiu,W.; Wang,X.; Leibowitz,B.; Yang,W.; Zhang,L.; Yu,J.Hepatology (Baltimore, Md.) 2011 ;54(4):1249-1258

p53 and PUMA independently regulate apoptosis of intestinal epithelial cells in patients and mice with colitisDirisina,R.; Katzman,R. B.; Goretsky,T.; Managlia,E.; Mittal,N.; Williams,D. B.; Qiu,W.; Yu,J.; Chandel,N. S.; Zhang,L.; Barrett,T. A.Gastroenterology 2011 ;141(3):1036-1045

Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21Leibowitz,B. J.; Qiu,W.; Liu,H.; Cheng,T.; Zhang,L.; Yu,J.Molecular cancer research : MCR 2011 ;9(5):616-625

Nanoscale nuclear architecture for cancer diagnosis beyond pathology via spatial-domain low-coherence quantitative phase microscopyWang,P.; Bista,R. K.; Khalbuss,W. E.; Qiu,W.; Uttam,S.; Staton,K.; Zhang,L.; Brentnall,T. A.; Brand,R. E.; Liu,Y.Journal of Biomedical Optics 2010 ;15(6):066028

An insight into statistical refractive index properties of cell internal structure via low-coherence statistical amplitude microscopyWang,P.; Bista,R. K.; Qiu,W.; Khalbuss,W. E.; Zhang,L.; Brand,R. E.; Liu,Y.Optics express 2010 ;18(21):21950-21958

Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K/AKT/p53 axisQiu,W.; Leibowitz,B.; Zhang,L.; Yu,J.Oncogene 2010 ;29(11):1622-1632

Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosisQiu,W.; Wang,X.; Leibowitz,B.; Liu,H.; Barker,N.; Okada,H.; Oue,N.; Yasui,W.; Clevers,H.; Schoen,R. E.; Yu,J.; Zhang,L.Proceedings of the National Academy of Sciences of the United States of America 2010 ;107(46):20027-20032

Dynamic change of Adamalysin 19 (ADAM19) in human placentas and its effects on cell invasion and adhesion in human trophoblastic cellsZhao,M.; Qiu,W.; Li,Y.; Sang,Q. A.; Wang,Y.Science in China.Series C, Life sciences / Chinese Academy of Sciences 2009 ;52(8):710-718

PUMA suppresses intestinal tumorigenesis in miceQiu,W.; Carson-Walter,E. B.; Kuan,S. F.; Zhang,L.; Yu,J.Cancer research 2009 ;69(12):4999-5006

PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosisWang,P.; Qiu,W.; Dudgeon,C.; Liu,H.; Huang,C.; Zambetti,G. P.; Yu,J.; Zhang,L.Cell death and differentiation 2009 ;16(9):1192-1202

PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndromeQiu,W.; Carson-Walter,E. B.; Liu,H.; Epperly,M.; Greenberger,J. S.; Zambetti,G. P.; Zhang,L.; Yu,J.Cell stem cell 2008 ;2(6):576-583

p53 independent induction of PUMA mediates intestinal apoptosis in response to ischaemia-reperfusionWu,B.; Qiu,W.; Wang,P.; Yu,H.; Cheng,T.; Zambetti,G. P.; Zhang,L.; Yu,J.Gut 2007 ;56(5):645-654

Immortalization of normal human cytotrophoblast cells by reconstitution of telomeric reverse transcriptase activityWang,Y. L.; Qiu,W.; Feng,H. C.; Li,Y. X.; Zhuang,L. Z.; Wang,Z.; Liu,Y.; Zhou,J. Q.; Zhang,D. H.; Tsao,G. S.Molecular human reproduction 2006 ;12(7):451-460

Dual effect of transforming growth factor beta1 on cell adhesion and invasion in human placenta trophoblast cellsZhao,M. R.; Qiu,W.; Li,Y. X.; Zhang,Z. B.; Li,D.; Wang,Y. L.Reproduction (Cambridge, England) 2006 ;132(2):333-341

Spatio-temporal expression of matrix metalloproteinase-26 in human placental trophoblasts and fetal red cells during normal placentationQiu,W.; Bai,S. X.; Zhao,M. R.; Wu,X. Q.; Zhao,Y. G.; Sang,Q. X.; Wang,Y. L.Biology of reproduction 2005 ;72(4):954-959

Temporal and spatial expression of integrins and their extracellular matrix ligands at the maternal-fetal interface in the rhesus monkey during pregnancyQin,L.; Wang,Y. L.; Bai,S. X.; Ji,S. H.; Qiu,W.; Tang,S.; Piao,Y. S.Biology of reproduction 2003 ;69(2):563-571