Patrick Stiff
M.D.
Coleman Professor of Oncology
Director, Cancer Center
FCO Division Director, Hematology/Oncology
Medical Director, Cancer Center
Hematology/Oncology
Pathology
CONTACT INFORMATION
Specialties
Leukemia, Ovarian Cancer, Non-Hodgkin's Lymphoma, Bone Marrow Transplantation
Locations
Board Certifications
Hematology - Subspecialty Cert: AM Board of Internal Medicine
Internal Medicine - General Cert: AM Board of Internal Medicine
Medical Oncology - Subspecialty Cert: AM Board of Internal Medicine
Publications
Michaelis,L. C.; Saad,A.; Zhong,X.; Le-Rademacher,J.; Freytes,C. O.; Marks,D. I.; Lazarus,H. M.; Bird,J. M.; Holmberg,L.; Kamble,R. T.; Kumar,S.; Lill,M.; Meehan,K. R.; Saber,W.; Schriber,J.; Tay,J.; Vogl,D. T.; Wirk,B.; Savani,B. N.; Gale,R. P.; Vesole,D. H.; Schiller,G. J.; Abidi,M.; Anderson,K. C.; Nishihori,T.; Kalaycio,M. E.; Vose,J. M.; Moreb,J. S.; Drobyski,W.; Munker,R.; Roy,V.; Ghobadi,A.; Holland,H. K.; Nath,R.; To,L. B.; Maiolino,A.; Kassim,A. A.; Giralt,S. A.; Landau,H.; Schouten,H. C.; Maziarz,R. T.; Michael,J.; Kindwall-Keller,T.; Stiff,P. J.; Gibson,J.; Lonial,S.; Krishnan,A.; Dispenzieri,A.; Hari,P.; Plasma Cell Disorders Working Committee of the Center for International Blood and Marrow Transplant ResearchSalvage Second Hematopoietic Cell Transplantation in Myeloma Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2013 ;19(5):760-766
Stiff,P. J.; Czerlanis,C.; Drakes,M. L.Dendritic cell immunotherapy in ovarian cancer Expert Review of Anticancer Therapy 2013 ;13(1):43-53
Beaudette-Zlatanova,B. C.; Le,P. T.; Knight,K. L.; Zhang,S.; Zakrzewski,S.; Parthasarathy,M.; Stiff,P. J.A potential role for B cells in suppressed immune responses in cord blood transplant recipients Bone marrow transplantation 2013 ;48(1):85-93
Mumby,P. B.; Hurley,C.; Samsi,M.; Thilges,S.; Parthasarathy,M.; Stiff,P. J.Predictors of non-compliance in autologous hematopoietic SCT patients undergoing out-patient transplants. Bone marrow transplantation 2012 ;47(4):556-561
Beaudette-Zlatanova,B. C.; Knight,K. L.; Zhang,S.; Stiff,P. J.; Zuniga-Pflucker,J. C.; Le,P. T.A human thymic epithelial cell culture system for the promotion of lymphopoiesis from hematopoietic stem cells. Experimental hematology 2011 ;39(5):570-579
Gerds,A.; Fox-Geiman,M.; Dawravoo,K.; Rodriguez,T.; Toor,A.; Smith,S.; Kiley,K.; Fletcher-Gonzalez,D.; Hicks,C.; Stiff,P.Randomized phase III trial of pegfilgrastim versus filgrastim after autologus peripheral blood stem cell transplantation. Biology of Blood & Marrow Transplantation 2010 ;16(5):678-685
Mumby,P. B.; Garcia,C.; Trivedi-Purohit,R.; Gourvitz,R.; Rychlik,K.; Rodriguez,T.; Smith,S. E.; Toor,A. A.; Rao,M.; Stiff,P. J.The impact of pharmacotherapy on depression and quality of life in patients undergoing a bone marrow transplant (BMT). ASCO Meeting Abstracts 2010 ;28(15_suppl):9132
Stiff,P. J.; Agovi,M. A.; Antman,K. H.; Blaise,D.; Camitta,B. M.; Cairo,M. S.; Childs,R. W.; Edwards,J. R.; Gale,R. P.; Hale,G. A.; Lazarus,H. M.; Arora,M.High-dose chemotherapy with blood or bone marrow transplants for rhabdomyosarcoma. Biology of Blood & Marrow Transplantation 2010 ;16(4):525-532
Stiff,P. J.; Bensinger,W.; Abidi,M. H.; Gingrich,R.; Artz,A. S.; Nademanee,A.; Hansen,K. S.; Sobczak,C.; Cutler,C.; Bolwell,B.; Shore,T. B.; Lazarus,H. M.; Yeager,A. M.; Lovelace,W.; Guo,M.; Dreiling,L.Clinical and ultrasonic evaluation of spleen size during peripheral blood progenitor cell mobilization by filgrastim: results of an open-label trial in normal donors. Biology of Blood & Marrow Transplantation 2009 ;15(7):827-834
Drakes,M. L.; Stiff,P. J.; Blanchard,T. G.Inverse relationship between dendritic cell CCR9 expression and maturation state. Immunology 2009 ;127(4):466-476
Stiff,P.; Micallef,I.; McCarthy,P.; Magalhaes-Silverman,M.; Weisdorf,D.; Territo,M.; Badel,K.; Calandra,G.Treatment with plerixafor in non-Hodgkin's lymphoma and multiple myeloma patients to increase the number of peripheral blood stem cells when given a mobilizing regimen of G-CSF: implications for the heavily pretreated patient. Biology of Blood & Marrow Transplantation 2009 ;15(2):249-256
Stiff,P. J.Managing hematopoietic stem-cell transplant resources: the case for outpatient transplantation Leukemia & lymphoma 2009 ;50(1):6-7
Guo,Y.; Niu,C.; Breslin,P.; Tang,M.; Zhang,S.; Wei,W.; Kini,A. R.; Paner,G. P.; Alkan,S.; Morris,S. W.; Diaz,M.; Stiff,P. J.; Zhang,J.c-Myc-mediated control of cell fate in megakaryocyte-erythrocyte progenitors. Blood 2009 ;114(10):2097-2106
Toor,A.; Rodriguez,T.; Bauml,M.; Mathews,H.; Shanti,S.; Senitzer,D.; Kini,A.; Norton,J.; Parthasarathy,M.; Mohideen,N.; Petrowsky,C.; Bonilla,B.; Smith,S.; Stiff,P.Feasibility of conditioning with thymoglobulin and reduced intensity TBI to reduce acute GVHD in recipients of allogeneic SCT. Bone marrow transplantation 2008 ;42(11):723-731
Stiff,P. J.Mucositis: continuing progress for a continuing need The Journal of Supportive Oncology 2007 ;5(4 Suppl 2):47-62
Toor,A. A.; Stiff,P. J.; Nickoloff,B. J.; Rodriguez,T.; Klein,J. L.; Gordon,K. B.Alefacept in corticosteroid refractory graft versus host disease: early results indicate promising activity. Journal of Dermatological Treatment 2007 ;18(1):13-18
Mullane,K.; Toor,A. A.; Kalnicky,C.; Rodriguez,T.; Klein,J.; Stiff,P.Posaconazole salvage therapy allows successful allogeneic hematopoietic stem cell transplantation in patients with refractory invasive mold infections. Transplant Infectious Disease 2007 ;9(2):89-96
Hofmeister,C. C.; Zhang,J.; Knight,K. L.; Le,P.; Stiff,P. J.Ex vivo expansion of umbilical cord blood stem cells for transplantation: growing knowledge from the hematopoietic niche Bone marrow transplantation 2007 ;39(1):11-23
Hofmeister,C. C.; Czerlanis,C.; Forsythe,S.; Stiff,P. J.Retrospective utility of bronchoscopy after hematopoietic stem cell transplant. Bone marrow transplantation 2006 ;38(10):693-698
Stiff,P. J.; Emmanouilides,C.; Bensinger,W. I.; Gentile,T.; Blazar,B.; Shea,T. C.; Lu,J.; Isitt,J.; Cesano,A.; Spielberger,R.Palifermin reduces patient-reported mouth and throat soreness and improves patient functioning in the hematopoietic stem-cell transplantation setting Journal of Clinical Oncology 2006 ;24(33):5186-5193
Stiff,P. J.; Erder,H.; Bensinger,W. I.; Emmanouilides,C.; Gentile,T.; Isitt,J.; Lu,Z. J.; Spielberger,R.Reliability and validity of a patient self-administered daily questionnaire to assess impact of oral mucositis (OM) on pain and daily functioning in patients undergoing autologous hematopoietic stem cell transplantation (HSCT). Bone marrow transplantation 2006 ;37(4):393-401
Stiff,P. J.; Miller,L. A.; Mumby,P.; Kiley,K.; Batiste,R.; Porter,N.; Potocki,K.; Volle,M.; Lichtenstein,S.; Wojtowicz,S.; Zakrzewski,S.; Toor,A.; Rodriguez,T.Patients' understanding of disease status and treatment plan at initial hematopoietic stem cell transplantation consultation. Bone marrow transplantation 2006 ;37(5):479-484
Stiff,P. J.Oral mucositis therapy comes of age Journal of Supportive Oncology 2005 ;3(2):73-75
Tanvetyanon,T.; Stiff,P. J.Recurrent steroid-responsive pancreatitis associated with myelodysplastic syndrome and transformations. Leukemia & lymphoma 2005 ;46(1):151-154
Hofmeister,C. C.; Stiff,P. J.Mucosal protection by cytokines. Current Hematology Reports 2005 ;4(6):446-453
Duus,J. E.; Stiff,P. J.; Choi,J.; Parthasarathy,M.; Rodriguez,T.; Toor,A. A.Second allografts for relapsed hematologic malignancies: feasibility of using a different donor. Bone marrow transplantation 2005 ;35(3):261-264
Toor,A. A.; Ayers,J.; Strupeck,J.; Parthasarathy,M.; Creech,S.; Rodriguez,T.; Stiff,P. J.Favourable results with a single autologous stem cell transplant following conditioning with busulphan and cyclophosphamide in patients with multiple myeloma. British journal of haematology 2004 ;124(6):769-776
Hofmeister,C. C.; Quinn,A.; Cooke,K. R.; Stiff,P.; Nickoloff,B.; Ferrara,J. L.Graft-versus-host disease of the skin: life and death on the epidermal edge Biology of Blood & Marrow Transplantation 2004 ;10(6):366-372
Tanvetyanon,T.; Toor,A. A.; Stiff,P. J.Post-transplant air-leak syndrome. British journal of haematology 2004 ;126(6):758
Boeve,S.; Strupeck,J.; Creech,S.; Stiff,P. J.Analysis of remobilization success in patients undergoing autologous stem cell transplants who fail an initial mobilization: risk factors, cytokine use and cost. Bone marrow transplantation 2004 ;33(10):997-1003
Stiff,P. J.; Shpall,E. J.; Liu,P. Y.; Wilczynski,S. P.; Callander,N. S.; Scudder,S. A.; Jazieh,A. R.; Samlowski,W.; McCoy,J.; Alberts,D. S.Randomized Phase II trial of two high-dose chemotherapy regimens with stem cell transplantation for the treatment of advanced ovarian cancer in first remission or chemosensitive relapse: a Southwest Oncology Group study. Gynecologic oncology 2004 ;94(1):98-106
Stiff,P. J.; Unger,J. M.; Forman,S. J.; McCall,A. R.; LeBlanc,M.; Nademanee,A. P.; Bolwell,B. J.; Fisher,R. I.The value of augmented preparative regimens combined with an autologous bone marrow transplant for the management of relapsed or refractory Hodgkin disease: a Southwest Oncology Group phase II trial. Biology of Blood & Marrow Transplantation 2003 ;9(8):529-539
Rodriguez,T. E.; Stiff,P. J.Current treatment results of allogeneic bone marrow transplantation for acute myeloid and lymphoid leukemia Current Hematology Reports 2003 ;2(4):295-301
Cooney,J. P.; Stiff,P. J.; Toor,A. A.; Parthasarathy,M.BEAM allogeneic transplantation for patients with Hodgkin's disease who relapse after autologous transplantation is safe and effective. Biology of Blood & Marrow Transplantation 2003 ;9(3):177-182
Education
Medical School
Loyola University Chicago Stritch School of Medicine
Residency
Cleveland Clinic Foundation, Internal Medicine: General
Fellowship
Memorial Sloan-Kettering Cancer Center, Internal Medicine: Hematology & Medical Oncology
Interests & Hobbies
Classical Music
Foreign Travel