James Cook
  • Professor
  • Co-Director, Infectious Disease and Immunology Research Institute
  • Division Director, Infectious Disease
  • Infectious Disease
TB and nontuberculous mycobacterial infections
Board Certifications
  • Infectious Disease - Subspecialty Cert: AM Board of Internal Medicine
  • Internal Medicine - General Cert: AM Board of Internal Medicine

Structural and biological evaluation of a novel series of benzimidazole inhibitors of Francisella tularensis enoyl-ACP reductase (FabI)Mehboob,S.; Song,J.; Hevener,K. E.; Su,P. C.; Boci,T.; Brubaker,L.; Truong,L.; Mistry,T.; Deng,J.; Cook,J. L.; Santarsiero,B. D.; Ghosh,A. K.; Johnson,M. E.Bioorganic & medicinal chemistry letters 2015 ;25(6):1292-1296

Clinical Significance of MYC Expression and/or "High-grade" Morphology in Non-Burkitt, Diffuse Aggressive B-cell Lymphomas: A SWOG S9704 Correlative StudyCook,J. R.; Goldman,B.; Tubbs,R. R.; Rimsza,L.; Leblanc,M.; Stiff,P.; Fisher,R.The American Journal of Surgical Pathology 2014 ;38(4):494-501

Autologous transplantation as consolidation for aggressive non-Hodgkin's lymphomaStiff,P. J.; Unger,J. M.; Cook,J. R.; Constine,L. S.; Couban,S.; Stewart,D. A.; Shea,T. C.; Porcu,P.; Winter,J. N.; Kahl,B. S.; Miller,T. P.; Tubbs,R. R.; Marcellus,D.; Friedberg,J. W.; Barton,K. P.; Mills,G. M.; LeBlanc,M.; Rimsza,L. M.; Forman,S. J.; Fisher,R. I.The New England journal of medicine 2013 ;369(18):1681-1690

Adenovirus E1B 19K Protein Modulates Innate Immunity through Apoptotic MimicryRadke,J. R.; Grigera,F.; Ucker,D. S.; Cook,J. L.Journal of virology 2013 ; ( ):

Continuation of long-term care for cervical dystonia at an academic movement disorders clinicGill,C. E.; Manus,N. D.; Pelster,M. W.; Cook,J. A.; Title,W.; Molinari,A. L.; Charles,D.Toxins 2013 ;5(4):776-783

Discovery of a novel and potent class of F. tularensis enoyl-reductase (FabI) inhibitors by molecular shape and electrostatic matching.Hevener,K. E.; Mehboob,S.; Su,P. C.; Truong,K.; Boci,T.; Deng,J.; Ghassemi,M.; Cook,J. L.; Johnson,M. E.Journal of medicinal chemistry 2012 ;55(1):268-279

Anthrax lethal factor activates K(+) channels to induce IL-1beta secretion in macrophages.Thomas,J.; Epshtein,Y.; Chopra,A.; Ordog,B.; Ghassemi,M.; Christman,J. W.; Nattel,S.; Cook,J. L.; Levitan,I.Journal of Immunology 2011 ;186(9):5236-5243

Nontuberculous mycobacteria: opportunistic environmental pathogens for predisposed hostsCook,J. L.British medical bulletin 2010 ;96( ):45-59

The recovery education in the academy program: transforming academic curricula with the principles of recovery and self-determinationRazzano,L. A.; Jonikas,J. A.; Goelitz,M. A.; Hamilton,M. M.; Marvin,R.; Jones-Martinez,N.; Ortiz,D.; Garrido,M.; Cook,J. A.Psychiatric rehabilitation journal 2010 ;34(2):130-136

Group A streptococcal necrotizing fasciitis of the eyelids and face managed with debridement and adjunctive intravenous immunoglobulin.Aakalu,V. K.; Sajja,K.; Cook,J. L.; Ahmad,A. Z.Ophthalmic Plastic & Reconstructive Surgery 2009 ;25(4):332-334

Design and synthesis of aryl ether inhibitors of the Bacillus anthracis enoyl-ACP reductase.Tipparaju,S. K.; Mulhearn,D. C.; Klein,G. M.; Chen,Y.; Tapadar,S.; Bishop,M. H.; Yang,S.; Chen,J.; Ghassemi,M.; Santarsiero,B. D.; Cook,J. L.; Johlfs,M.; Mesecar,A. D.; Johnson,M. E.; Kozikowski,A. P.ChemMedChem 2008 ;3(8):1250-1268

Nucleotide biosynthesis is critical for growth of bacteria in human blood.Samant,S.; Lee,H.; Ghassemi,M.; Chen,J.; Cook,J. L.; Mankin,A. S.; Neyfakh,A. A.PLoS Pathogens 2008 ;4(2):e37

Restoration of the antiviral activity of 3'-azido-3'-deoxythymidine (AZT) against AZT-resistant human immunodeficiency virus by delivery of engineered thymidylate kinase to T cells.Lavie,A.; Su,Y.; Ghassemi,M.; Novak,R. M.; Caffrey,M.; Sekulic,N.; Monnerjahn,C.; Konrad,M.; Cook,J. L.Journal of General Virology 2008 ;89(Pt 7):1672-1679

E1A oncogene enhancement of caspase-2-mediated mitochondrial injury sensitizes cells to macrophage nitric oxide-induced apoptosis.Radke,J. R.; Siddiqui,Z. K.; Miura,T. A.; Routes,J. M.; Cook,J. L.Journal of Immunology 2008 ;180(12):8272-8279

Field evaluation of digital optical method to quantify the visual opacity of plumes.Du,K.; Rood,M. J.; Kim,B. J.; Kemme,M. R.; Franek,B. J.; Mattison,K.; Cook,J.Journal of the Air & Waste Management Association 2007 ;57(7):836-844

Medical School
  • Baylor College of Medicine
  • University of Utah Hospital and Clinics, Internal Medicine: General
  • University of Utah Hospital and Clinics, Internal Medicine: Infectious Disease