CONTACT INFORMATION http://www.loyola.org
Holly Kramer
M.D.,M.P.H.
  • Associate Professor
  • Nephrology
  • Public Health Sciences
Specialties
Kidney Disorders, Kidney Stones, Prevention of End-Stage Kidney Disease
Board Certifications
  • Internal Medicine - General Cert: AM Board of Internal Medicine
  • Nephrology - Subspecialty Cert: AM Board of Internal Medicine
Research Summary

Research Interests: Obesity, kidney disease and genetic variants for kidney disease, intersection between kidney and cardiovascular disease

Publications

Bariatric Surgery: The Solution to a Big Problem?Alhosaini,M.; Leehey,D.; Kramer,H.American Journal of Kidney Diseases : The Official Journal of the National Kidney Foundation 2014 ; ( ):

Prevalence of risk of deficiency and inadequacy of 25-hydroxyvitamin D in US children: NHANES 2003-2006Karalius,V. P.; Zinn,D.; Wu,J.; Cao,G.; Minutti,C.; Luke,A.; Kramer,H.; Durazo-Arvizu,R.Journal of pediatric endocrinology & metabolism : JPEM 2014 ; ( ):

25-Hydroxyvitamin D Testing and Supplementation in CKD: An NKF-KDOQI Controversies ReportKramer,H.; Berns,J. S.; Choi,M. J.; Martin,K.; Rocco,M. V.American Journal of Kidney Diseases : The Official Journal of the National Kidney Foundation 2014 ; ( ):

Association of Albumin-Creatinine Ratio and Cystatin C With Change in Ankle-Brachial Index: The Multi-Ethnic Study of Atherosclerosis (MESA)Garimella,P. S.; Ix,J. H.; Katz,R.; Shlipak,M. G.; Criqui,M. H.; Siscovick,D. S.; Kramer,H.; Sibley,C. T.; Sarnak,M. J.American Journal of Kidney Diseases : The Official Journal of the National Kidney Foundation 2014 ; ( ):

Diet: the "keys" to longevityKramer,H.Clinical journal of the American Society of Nephrology : CJASN 2013 ;8(9):1469-1470

Dietary patterns, calories, and kidney diseaseKramer,H.Advances in Chronic Kidney Disease 2013 ;20(2):135-140

Is there a reverse J-shaped association between 25-hydroxyvitamin D and all-cause mortality? Results from the U.S. nationally representative NHANESSempos,C. T.; Durazo-Arvizu,R. A.; Dawson-Hughes,B.; Yetley,E. A.; Looker,A. C.; Schleicher,R. L.; Cao,G.; Burt,V.; Kramer,H.; Bailey,R. L.; Dwyer,J. T.; Zhang,X.; Gahche,J.; Coates,P. M.; Picciano,M. F.The Journal of clinical endocrinology and metabolism 2013 ;98(7):3001-3009

Genetic variation in APOL1 and MYH9 genes is associated with chronic kidney disease among NigeriansTayo,B. O.; Kramer,H.; Salako,B. L.; Gottesman,O.; McKenzie,C. A.; Ogunniyi,A.; Bottinger,E. P.; Cooper,R. S.International Urology and Nephrology 2013 ;45(2):485-494

Moving Dietary Management of Diabetes ForwardKramer,H.; Chang,A.JAMA internal medicine 2013 ; ( ):

Race and the insulin resistance syndromeKramer,H.; Dugas,L.; Rosas,S. E.Seminars in nephrology 2013 ;33(5):457-467

Obesity as an effect modifier of the risk of death in chronic kidney diseaseKramer,H.; Dugas,L.; Shoham,D.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2013 ; ( ):

Obesity and kidney disease: potential mechanismsWickman,C.; Kramer,H.Seminars in nephrology 2013 ;33(1):14-22

Metabolic Subtypes and Risk of Mortality in Normal Weight, Overweight, and Obese Individuals with CKDHanks,L. J.; Tanner,R. M.; Muntner,P.; Kramer,H.; McClellan,W. M.; Warnock,D. G.; Judd,S. E.; Gutierrez,O. M.; on behalf of the REGARDS InvestigatorsClinical journal of the American Society of Nephrology : CJASN 2013 ; ( ):

Mortality rates across 25-hydroxyvitamin D (25[OH]D) levels among adults with and without estimated glomerular filtration rate <60 ml/min/1.73 m2: the third national health and nutrition examination surveyKramer,H.; Sempos,C.; Cao,G.; Luke,A.; Shoham,D.; Cooper,R.; Durazo-Arvizu,R.PLoS ONE 2012 ;7(10):e47458

Patterns of sodium and potassium excretion and blood pressure in the African DiasporaTayo,B. O.; Luke,A.; McKenzie,C. A.; Kramer,H.; Cao,G.; Durazo-Arvizu,R.; Forrester,T.; Adeyemo,A. A.; Cooper,R. S.Journal of human hypertension 2012 ;26(5):315-324

Medium and long-term outcomes after pneumatic dilation or laparoscopic Heller myotomy for achalasia: a meta-analysisWeber,C. E.; Davis,C. S.; Kramer,H. J.; Gibbs,J. T.; Robles,L.; Fisichella,P. M.Surgical laparoscopy, endoscopy & percutaneous techniques 2012 ;22(4):289-296

Association of carotid intima-media thickness with progression of urine albumin-creatinine ratios in The Multi-Ethnic Study of Atherosclerosis (MESA).Yu,Z.; Schneck,M.; Jacobs,D. R.,Jr; Liu,K.; Allison,M.; O'Leary,D.; Durazo,R.; Darwin,C.; Kramer,H.American Journal of Kidney Diseases 2011 ;57(1):62-70

The effect of including cystatin C or creatinine in a cardiovascular risk model for asymptomatic individuals: the multi-ethnic study of atherosclerosis.Ito,H.; Pacold,I. V.; Durazo-Arvizu,R.; Liu,K.; Shilipak,M. G.; Goff,D. C.,Jr; Tracy,R. P.; Kramer,H.American Journal of Epidemiology 2011 ;174(8):949-957

Patterns of sodium and potassium excretion and blood pressure in the African DiasporaTayo,B. O.; Luke,A.; McKenzie,C. A.; Kramer,H.; Cao,G.; Durazo-Arvizu,R.; Forrester,T.; Adeyemo,A. A.Journal of human hypertension 2011 ; ( ):

Association of Waist Circumference and Body Mass Index With All-Cause Mortality in CKD: The REGARDS (Reasons for Geographic and Racial Differences in Stroke) StudyKramer,H.; Shoham,D.; McClure,L. A.; Durazo-Arvizu,R.; Howard,G.; Judd,S.; Muntner,P.; Safford,M.; Warnock,D. G.; McClellan,W.American Journal of Kidney Diseases 2011 ;58(2):177-185

The National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (KDOQI) Grant Initiative: moving clinical practice forward.Kramer,H.American Journal of Kidney Diseases 2010 ;55(3):411-414

Increasing BMI and waist circumference and prevalence of obesity among adults with Type 2 diabetes: the National Health and Nutrition Examination SurveysKramer,H.; Cao,G.; Dugas,L.; Luke,A.; Cooper,R.; Durazo-Arvizu,R. A.Journal of diabetes and its complications 2010 ;24(6):368-374

Can comprehensive lifestyle change alter the course of chronic kidney disease?Tuttle,K. R.; Sunwold,D.; Kramer,H.Seminars in nephrology 2009 ;29(5):512-523

Obesity and albuminuria among adults with type 2 diabetes: the Look AHEAD (Action for Health in Diabetes) Study.Kramer,H.; Reboussin,D.; Bertoni,A. G.; Marcovina,S.; Lipkin,E.; Greenway,F. L.,3rd; Brancati,F. L.Diabetes care 2009 ;32(5):851-853

Obesity management in adults with CKDKramer,H.; Tuttle,K. R.; Leehey,D.; Luke,A.; Durazo-Arvizu,R.; Shoham,D.; Cooper,R.; Beddhu,S.American Journal of Kidney Diseases 2009 ;53(1):151-165

Chronic kidney disease prevalence estimates among racial/ethnic groups: the Multi-Ethnic Study of Atherosclerosis.Kramer,H.; Palmas,W.; Kestenbaum,B.; Cushman,M.; Allison,M.; Astor,B.; Shlipak,M.Clinical Journal of The American Society of Nephrology: CJASN 2008 ;3(5):1391-1397

Association of mild to moderate kidney dysfunction and coronary calcification.Ix,J. H.; Katz,R.; Kestenbaum,B.; Fried,L. F.; Kramer,H.; Stehman-Breen,C.; Shlipak,M. G.Journal of the American Society of Nephrology 2008 ;19(3):579-585

Ethnicity and sex modify the association of serum c-reactive protein with microalbuminuria.Palmas,W.; Ma,S.; Jacobs,D. R.,Jr; Arnett,D.; Jackson,S.; Olson,J.; Saad,M. F.; Kronmal,R.; Kramer,H.; Barr,R. G.Ethnicity & disease 2008 ;18(3):324-329

Sugary soda consumption and albuminuria: results from the National Health and Nutrition Examination Survey, 1999-2004.Shoham,D. A.; Durazo-Arvizu,R. A.; Kramer,H.; Luke,A.; Vupputuri,S.; Kshirsagar,A.PLoS ONE [Electronic Resource] 2008 ;3(10):e3431

Mild elevations of urine albumin excretion are associated with atherogenic lipoprotein abnormalities in the Multi-Ethnic Study of Atherosclerosis (MESA).de Boer,I. H.; Astor,B. C.; Kramer,H.; Palmas,W.; Rudser,K.; Seliger,S. L.; Shlipak,M. G.; Siscovick,D. S.; Tsai,M. Y.; Kestenbaum,B.Atherosclerosis 2008 ;197(1):407-414

Lipoprotein abnormalities associated with mild impairment of kidney function in the multi-ethnic study of atherosclerosis.de Boer,I. H.; Astor,B. C.; Kramer,H.; Palmas,W.; Seliger,S. L.; Shlipak,M. G.; Siscovick,D. S.; Tsai,M. Y.; Kestenbaum,B.Clinical Journal of The American Society of Nephrology: CJASN 2008 ;3(1):125-132

Urinary incontinence prevalence: results from the National Health and Nutrition Examination Survey.Dooley,Y.; Kenton,K.; Cao,G.; Luke,A.; Durazo-Arvizu,R. A.; Kramer,H.; Brubaker,L.Journal of Urology 2008 ;179(2):656-661

Adverse renal consequences of obesityGriffin,K. A.; Kramer,H.; Bidani,A. K.American Journal of Physiology - Renal Physiology 2008 ;294(4):F685-96

Metabolic syndrome and self-reported history of kidney stones: the National Health and Nutrition Examination Survey (NHANES III) 1988-1994.West,B.; Luke,A.; Durazo-Arvizu,R. A.; Cao,G.; Shoham,D. A.; Kramer,H.American Journal of Kidney Diseases 2008 ;51(5):741-747

Regional left ventricular function in individuals with mild to moderate renal insufficiency: the Multi-Ethnic Study of Atherosclerosis.Nasir,K.; Rosen,B. D.; Kramer,H. J.; Edvardsen,T.; Bluemke,D. A.; Liu,K.; Lima,J. A.American Heart Journal 2007 ;153(4):545-551

Acculturation is associated with hypertension in a multiethnic sample.Moran,A.; Roux,A. V.; Jackson,S. A.; Kramer,H.; Manolio,T. A.; Shrager,S.; Shea,S.American Journal of Hypertension 2007 ;20(4):354-363

Ethnicity, energy expenditure and obesity: are the observed black/white differences meaningful?Luke,A.; Dugas,L.; Kramer,H.Current Opinion in Endocrinology, Diabetes & Obesity 2007 ;14(5):370-373

Prevalence and impact of nocturia in a urogynecologic population.Lowenstein,L.; Brubaker,L.; Kenton,K.; Kramer,H.; Shott,S.; FitzGerald,M. P.International Urogynecology Journal 2007 ;18(9):1049-1052

Obesity and kidney disease: a big dilemmaKramer,H.; Luke,A.Current Opinion in Nephrology & Hypertension 2007 ;16(3):237-241

Obesity and chronic kidney diseaseKramer,H.Contributions to nephrology 2006 ;151( ):1-18

Increasing body mass index and obesity in the incident ESRD population.Kramer,H. J.; Saranathan,A.; Luke,A.; Durazo-Arvizu,R. A.; Guichan,C.; Hou,S.; Cooper,R.Journal of the American Society of Nephrology 2006 ;17(5):1453-1459

Dyslipidemia prevalence, treatment, and control in the Multi-Ethnic Study of Atherosclerosis (MESA): gender, ethnicity, and coronary artery calciumGoff,D. C.,Jr; Bertoni,A. G.; Kramer,H.; Bonds,D.; Blumenthal,R. S.; Tsai,M. Y.; Psaty,B. M.Circulation 2006 ;113(5):647-656

Progression of kidney disease in type 2 diabetes - beyond blood pressure control: an observational study.Leehey,D. J.; Kramer,H. J.; Daoud,T. M.; Chatha,M. P.; Isreb,M. A.BMC Nephrology 2005 ;6(1):8

Relationship between blood pressure and physical activity assessed with stable isotopes.Luke,A.; Kramer,H.; Adeyemo,A.; Forrester,T.; Wilks,R.; Schoeller,D.; Leman,C.Journal of human hypertension 2005 ;19(2):127-132

Screening for kidney disease in adults with diabetes and prediabetesKramer,H.Current Opinion in Nephrology & Hypertension 2005 ;14(3):249-252

Urine albumin excretion and subclinical cardiovascular disease. The Multi-Ethnic Study of AtherosclerosisKramer,H.; Jacobs,D. R.,Jr; Bild,D.; Post,W.; Saad,M. F.; Detrano,R.; Tracy,R.; Cooper,R.; Liu,K.Hypertension 2005 ;46(1):38-43

Obesity and prevalent and incident CKD: the Hypertension Detection and Follow-Up Program.Kramer,H.; Luke,A.; Bidani,A. K.; Cao,G.; Cooper,R.; McGee,D.American Journal of Kidney Diseases 2005 ;46(4):587-594

Screening for kidney disease in adults with diabetes.Kramer,H.; Molitch,M. E.Diabetes care 2005 ;28(7):1813-1816

Association between chronic kidney disease and coronary artery calcification: the Dallas Heart Study.Kramer,H.; Toto,R.; Peshock,R.; Cooper,R.; Victor,R.Journal of the American Society of Nephrology 2005 ;16(2):507-513

Angiotensin-converting enzyme gene polymorphisms and obesity: an examination of three black populations.Kramer,H.; Wu,X.; Kan,D.; Luke,A.; Zhu,X.; Adeyemo,A.; McKenzie,C.; Cooper,R.Obesity research 2005 ;13(5):823-828

A randomized trial on sodium reduction in two developing countries.Forrester,T.; Adeyemo,A.; Soarres-Wynter,S.; Sargent,L.; Bennett,F.; Wilks,R.; Luke,A.; Prewitt,E.; Kramer,H.Journal of human hypertension 2005 ;19(1):55-60

Hypertension treatment and control in five European countries, Canada, and the United States.Wolf-Maier,K.; Kramer,H.; Banegas,J. R.; Giampaoli,S.; Joffres,M. R.; Poulter,N.; Primatesta,P.; Stegmayr,B.; Thamm,M.Hypertension 2004 ;43(1):10-17

Screening for kidney disease in adults with diabetes mellitus: don't forget serum creatinine.[comment]Kramer,H.American Journal of Kidney Diseases 2004 ;44(5):921-923

Racial/ethnic differences in hypertension and hypertension treatment and control in the multi-ethnic study of atherosclerosis (MESA).Kramer,H.; Han,C.; Post,W.; Goff,D.; Diez-Roux,A.; Cooper,R.; Jinagouda,S.; Shea,S.American Journal of Hypertension 2004 ;17(10):963-970

Association between blood pressure and resting energy expenditure independent of body sizeLuke,A.; Adeyemo,A.; Kramer,H.; Forrester,T.Hypertension 2004 ;43(3):555-560

Comparison of three tacrolimus-based immunosuppressive regimens in lung transplantation.Bhorade,S. M.; Jordan,A.; Villanueva,J.; Yu,A.; Kramer,H.; Vigneswaran,W. T.; Garrity,E. R.American Journal of Transplantation 2003 ;3(12):1570-1575

Hemodialysis and estrogen levels in postmenopausal (HELP) patients: The multicenter HELP study.Kramer,H. M.; Curhan,G.; Singh,A.American Journal of Kidney Diseases 2003 ;41(6):1240-1246

Permanent cessation of menses and postmenopausal hormone use in dialysis-dependent women: the HELP study.Kramer,H. M.; Curhan,G. C.; Singh,A.American Journal of Kidney Diseases 2003 ;41(3):643-650

High-normal blood pressure and microalbuminuria.Knight,E. L.; Kramer,H. M.; Curhan,G. C.American Journal of Kidney Diseases 2003 ;41(3):588-595

The association between gout and nephrolithiasis in men: The Health Professionals' Follow-Up Study.Kramer,H. J.; Choi,H. K.; Atkinson,K.; Stampfer,M.; Curhan,G. C.Kidney international 2003 ;64(3):1022-1026

Renal insufficiency in the absence of albuminuria and retinopathy among adults with type 2 diabetes mellitusKramer,H. J.; Nguyen,Q. D.; Curhan,G.; Hsu,C. Y.JAMA 2003 ;289(24):3273-3277

The association between gout and nephrolithiasis: the National Health and Nutrition Examination Survey III, 1988-1994.Kramer,H. M.; Curhan,G.American Journal of Kidney Diseases 2002 ;40(1):37-42

Education
Medical School
  • Indiana University School of Medicine
Residency
  • Emory University School of Medicine, Internal Medicine: General
Fellowship
  • Harvard University Medical School Combined Nephrology Program, Internal Medicine: Nephrology
Biography

Dr. Kramer received her M.D. from the Indiana University School of Medicine. After completing a nephrology fellowship at Harvard University Medical School in 2002, Dr. Kramer was jointly appointed to the Department of Medicine, Division of Nephrology and Hypertension, and Department of Preventative Medicine at the Loyola University Medical Center. She became co-director (Dr. Durazo) of the Clinical Research Methods and Epidemiology Program in 2005, developing several courses for the program, and later became the program director for the Program Director for the MPH Program in 2009. As an investigator, Dr. Kramer’s research focuses on obesity and kidney disease and genetic variants for kidney disease and she is a co-investigator for the Multi-Ethnic Study of Atherosclerosis.

Interests
  • Outdoor Activities