David J. Wilber
  • George M. Eisenberg Professor of Cardiovascular Sciences
  • Co-Director, Cardiovascular Research Institute
  • Director, Cardiovascular Institute
  • Division Director, Cardiology
  • Medical Director, Clinical Electrophysiology
  • Cardiology
  • Pediatric Cardiology
Ablation of Atrial Fibrillation, Alternatives to Anticoagulation for AF, Heart Failure; Arrhythmias, Electrophysiology, Ablation Catheter Applications for Complex Arrhythmias
Board Certifications
  • Cardiovascular Disease - Subspecialty Cert: AM Board of Internal Medicine
  • Clinical Cardiac Electrophysiology - Subspecialty Cert: AM Board of Internal Medicine
  • Internal Medicine - General Cert: AM Board of Internal Medicine

Left atrial volume assessment in atrial fibrillation using multimodality imaging: a comparison of echocardiography, invasive three-dimensional CARTO and cardiac magnetic resonance imagingRabbat,M. G.; Wilber,D.; Thomas,K.; Malick,O.; Bashir,A.; Agrawal,A.; Biswas,S.; Sanagala,T.; Syed,M. A.The international journal of cardiovascular imaging 2015 ; ( ):

Uninterrupted rivaroxaban vs. uninterrupted vitamin K antagonists for catheter ablation in non-valvular atrial fibrillationCappato,R.; Marchlinski,F. E.; Hohnloser,S. H.; Naccarelli,G. V.; Xiang,J.; Wilber,D. J.; Ma,C. S.; Hess,S.; Wells,D. S.; Juang,G.; Vijgen,J.; Hugl,B. J.; Balasubramaniam,R.; De Chillou,C.; Davies,D. W.; Fields,L. E.; Natale,A.; VENTURE-AF InvestigatorsEUROPEAN HEART JOURNAL 2015 ; ( ):

Long-Term Mortality After Ablation of Ischemic Ventricular Tachycardia: Not Inducible Is Not EnoughWilber,D. J.Journal of the American College of Cardiology 2015 ; ( ):

Mortality Reduction In Relation To ICD Programming In MADIT-RITRuwald,A. C.; Schuger,C.; Moss,A. J.; Kutyifa,V.; Olshansky,B.; Greenberg,H.; Cannom,D. S.; Estes,N. A.,3rd; Ruwald,M. H.; Huang,D. T.; Klein,H.; McNitt,S.; Beck,C. A.; Goldstein,R.; Brown,M. W.; Kautzner,J.; Shoda,M.; Wilber,D.; Zareba,W.; Daubert,J. P.Circulation.Arrhythmia and electrophysiology 2014 ; ( ):

Paroxysmal AF Catheter Ablation With a Contact Force Sensing Catheter: Results of the Prospective, Multicenter SMART-AF TrialNatale,A.; Reddy,V. Y.; Monir,G.; Wilber,D. J.; Lindsay,B. D.; McElderry,H. T.; Kantipudi,C.; Mansour,M. C.; Melby,D. P.; Packer,D. L.; Nakagawa,H.; Zhang,B.; Stagg,R. B.; Boo,L. M.; Marchlinski,F. E.Journal of the American College of Cardiology 2014 ;64(7):647-656

Ablation of the Epicardial Substrate in Ventricular Tachycardia Associated with Structural Heart Disease: Outside In or Inside Out?Wilber,D. J.Journal of the American College of Cardiology 2014 ; ( ):

Survival with Cardiac-Resynchronization Therapy in Mild Heart FailureGoldenberg,I.; Kutyifa,V.; Klein,H. U.; Cannom,D. S.; Brown,M. W.; Dan,A.; Daubert,J. P.; Estes,N. A.,3rd; Foster,E.; Greenberg,H.; Kautzner,J.; Klempfner,R.; Kuniss,M.; Merkely,B.; Pfeffer,M. A.; Quesada,A.; Viskin,S.; McNitt,S.; Polonsky,B.; Ghanem,A.; Solomon,S. D.; Wilber,D.; Zareba,W.; Moss,A. J.The New England journal of medicine 2014 ; ( ):

Usefulness of Left Ventricular Diastolic Function to Predict Recurrence of Atrial Fibrillation in Patients With Preserved Left Ventricular Systolic FunctionHirai,T.; Cotseones,G.; Makki,N.; Agrawal,A.; Wilber,D. J.; Barron,J. T.The American Journal of Cardiology 2014 ; ( ):

Association of atrial tissue fibrosis identified by delayed enhancement MRI and atrial fibrillation catheter ablation: the DECAAF studyMarrouche,N. F.; Wilber,D.; Hindricks,G.; Jais,P.; Akoum,N.; Marchlinski,F.; Kholmovski,E.; Burgon,N.; Hu,N.; Mont,L.; Deneke,T.; Duytschaever,M.; Neumann,T.; Mansour,M.; Mahnkopf,C.; Herweg,B.; Daoud,E.; Wissner,E.; Bansmann,P.; Brachmann,J.JAMA : the journal of the American Medical Association 2014 ;311(5):498-506

Comparison of primary percutaneous coronary intervention in patients with st-elevation myocardial infarction during and prior to availability of an in-house STEMI system: Early experience and intermediate outcomes of the HARRT program for achieving routine d2b times <60 minutesNguyen,B.; Fennessy,M.; Leya,F.; Nowak,W.; Ryan,M.; Freeberg,S.; Gill,J.; Dieter,R. S.; Steen,L.; Lewis,B.; Cichon,M.; Probst,B.; Jarotkiewicz,M.; Wilber,D.; Lopez,J. J.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2014 ; ( ):

Catheter ablation of ventricular arrhythmias: targets, tactics, and toolsWinterfield,J. R.; Mahapatra,S.; Wilber,D. J.CURRENT OPINION IN CARDIOLOGY 2013 ;28(3):344-353

Comparison of two methods of right atrial volume assessment using cardiac magnetic resonance imaging: area-length method versus multislice volumetric methodBiswas,S.; Sanagala,T.; Wilber,D.; Syed,M. A.Journal of Cardiovascular Magnetic Resonance (BioMed Central) 2013 ;15( ):1-2

Left atrial volume assessment by area-length method compared to multislice volumetric method using cardiovascular magnetic resonance imagingBashir,A.; Rabbat,M.; Biswas,S.; Wilber,D.; Sanagala,T.; Syed,M. A.Journal of Cardiovascular Magnetic Resonance (BioMed Central) 2013 ;15( ):1-2

Safety of the Open-Irrigated Ablation Catheter for Radiofrequency Ablation: Safety Analysis from Six Clinical StudiesWaldo,A. L.; Wilber,D. J.; Marchlinski,F. E.; Stevenson,W. G.; Aker,B.; Boo,L. M.; Jackman,W. M.Pacing & Clinical Electrophysiology 2012 ;35(9):1081-1089

Fibroblasts, focal triggers, and persistent atrial fibrillation: is there a connection?Wilber,D. J.Circulation: Arrhythmia & Electrophysiology 2012 ;5(2):249-251

Venice Chart International Consensus Document on Atrial Fibrillation Ablation: 2011 UpdateRaviele,A.; Natale,A.; Calkins,H.; Camm,J. A.; Cappato,R.; Ann Chen,S.; Connolly,S. J.; Damiano Jr,R.; De Ponti,R.; Edgerton,J. R.; Haissaguerre,M.; Hindricks,G.; Ho,S. Y.; Jalife,J.; Kirchhof,P.; Kottkamp,H.; Kuck,K. H.; Marchlinski,F. E.; Packer,D. L.; Pappone,C.; Prystowsky,E.; Reddy,V. K.; Themistoclakis,S.; Verma,A.; Wilber,D. J.; Willems,S.Journal of cardiovascular electrophysiology 2012 ;23(8):890-923

Altered desmosomal proteins in granulomatous myocarditis and potential pathogenic links to arrhythmogenic right ventricular cardiomyopathyAsimaki,A.; Tandri,H.; Duffy,E. R.; Winterfield,J. R.; Mackey-Bojack,S.; Picken,M. M.; Cooper,L. T.; Wilber,D. J.; Marcus,F. I.; Basso,C.; Thiene,G.; Tsatsopoulou,A.; Protonotarios,N.; Stevenson,W. G.; McKenna,W. J.; Gautam,S.; Remick,D. G.; Calkins,H.; Saffitz,J. E.Circulation.Arrhythmia and electrophysiology 2011 ;4(5):743-752

Selective CFAE Targeting for Atrial Fibrillation Study (SELECT AF): Clinical Rationale, Design, and ImplementationVerma,A.; Sanders,P.; Macle,L.; Champagne,J.; Nair,G. M.; Calkins,H.; Wilber,D. J.Journal of cardiovascular electrophysiology 2011 ;22(5):541-547

Pericardial fat is independently associated with human atrial fibrillation.Al Chekakie,M. O.; Welles,C. C.; Metoyer,R.; Ibrahim,A.; Shapira,A. R.; Cytron,J.; Santucci,P.; Wilber,D. J.; Akar,J. G.Journal of the American College of Cardiology 2010 ;56(10):784-788

Comparison of antiarrhythmic drug therapy and radiofrequency catheter ablation in patients with paroxysmal atrial fibrillation: a randomized controlled trial.Wilber,D. J.; Pappone,C.; Neuzil,P.; De Paola,A.; Marchlinski,F.; Natale,A.; Macle,L.; Daoud,E. G.; Calkins,H.; Hall,B.; Reddy,V.; Augello,G.; Reynolds,M. R.; Vinekar,C.; Liu,C. Y.; Berry,S. M.; Berry,D. A.JAMA 2010 ;303(4):333-340

DeCFAEnating atrial fibrillation: narrowing the targets... complex and/or fractionated atrial electrogramWilber,D. J.Journal of cardiovascular electrophysiology 2010 ;21(6):617-619

Electroanatomic mapping of postpacing intervals clarifies the complete active circuit and variants in atrial flutter.Santucci,P. A.; Varma,N.; Cytron,J.; Akar,J. G.; Wilber,D. J.; Al Chekakie,M. O.; Brysiewicz,N.Heart Rhythm 2009 ;6(11):1586-1595

Electrophysiologic Testing for Risk Stratification Following Myocardial Infarction: Dead or Alive?WILBER,D. J.Journal of cardiovascular electrophysiology 2009 ;20(8):856-858

Prospective study of cardiac sarcoid mimicking arrhythmogenic right ventricular dysplasiaVasaiwala,S. C.; Finn,C.; Delpriore,J.; Leya,F.; Gagermeier,J.; Akar,J. G.; Santucci,P.; Dajani,K.; Bova,D.; Picken,M. M.; Basso,C.; Marcus,F.; Wilber,D. J.Journal of cardiovascular electrophysiology 2009 ;20(5):473-476

No benefit from defibrillation threshold testing in the SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial).Blatt,J. A.; Poole,J. E.; Johnson,G. W.; Callans,D. J.; Raitt,M. H.; Reddy,R. K.; Marchlinski,F. E.; Yee,R.; Guarnieri,T.; Talajic,M.; Wilber,D. J.; Anderson,J.; Chung,K.; Wong,W. S.; Mark,D. B.; Lee,K. L.; Bardy,G. H.Journal of the American College of Cardiology 2008 ;52(7):551-556

Prospective study of atrial fibrillation termination during ablation guided by automated detection of fractionated electrograms.Porter,M.; Spear,W.; Akar,J. G.; Helms,R.; Brysiewicz,N.; Santucci,P.; Wilber,D. J.Journal of cardiovascular electrophysiology 2008 ;19(6):613-620

Prognostic importance of defibrillator shocks in patients with heart failure.Poole,J. E.; Johnson,G. W.; Hellkamp,A. S.; Anderson,J.; Callans,D. J.; Raitt,M. H.; Reddy,R. K.; Marchlinski,F. E.; Yee,R.; Guarnieri,T.; Talajic,M.; Wilber,D. J.; Fishbein,D. P.; Packer,D. L.; Mark,D. B.; Lee,K. L.; Bardy,G. H.New England Journal of Medicine 2008 ;359(10):1009-1017

Endothelial dysfunction in heart failure identifies responders to cardiac resynchronization therapy.Akar,J. G.; Al Chekakie,M. O.; Fugate,T.; Moran,L.; Froloshki,B.; Varma,N.; Santucci,P.; Wilber,D. J.; Matsumura,M. E.Heart Rhythm 2008 ;5(9):1229-1235

Acute onset human atrial fibrillation is associated with local cardiac platelet activation and endothelial dysfunction.Akar,J. G.; Jeske,W.; Wilber,D. J.Journal of the American College of Cardiology 2008 ;51(18):1790-1793

Newly diagnosed arrhythmogenic right ventricular dysplasia in an octogenarian.Akar,J. G.; Singh,M.; Auseon,A. J.; Wilber,D. J.Journal of cardiovascular electrophysiology 2008 ;19(12):1316-1318

Surface electrocardiographic patterns and electrophysiologic characteristics of atrial flutter following modified radiofrequency MAZE proceduresAkar,J. G.; Al Chekakie,M. O.; Hai,A.; Brysiewicz,N.; Porter,M.; Varma,N.; Santucci,P.; Wilber,D. J.Journal of cardiovascular electrophysiology 2007 ;18(4):349-355

Ethanol septal ablation for refractory ventricular tachycardiaRamana,R. K.; Wilber,D. J.; Leya,F.Journal of Invasive Cardiology 2007 ;19(5):E142-5

The effects of statins and renin-angiotensin system blockers on atrial fibrillation recurrence following antral pulmonary vein isolationAl Chekakie,M. O.; Akar,J. G.; Wang,F.; Al Muradi,H.; Wu,J.; Santucci,P.; Varma,N.; Wilber,D. J.Journal of cardiovascular electrophysiology 2007 ;18(9):942-946

Substrate-based endocardial ablation of postinfarction ventricular tachycardiaOza,S.; Wilber,D. J.Heart Rhythm 2006 ;3(5):607-609

Idiopathic epicardial left ventricular tachycardia originating remote from the sinus of Valsalva: electrophysiological characteristics, catheter ablation, and identification from the 12-lead electrocardiogram.Daniels,D. V.; Lu,Y. Y.; Morton,J. B.; Santucci,P. A.; Akar,J. G.; Green,A.; Wilber,D. J.Circulation 2006 ;113(13):1659-1666

Spatial resolution of pacemapping and activation mapping in patients with idiopathic right ventricular outflow tract tachycardia.Azegami,K.; Wilber,D. J.; Arruda,M.; Lin,A. C.; Denman,R. A.Journal of cardiovascular electrophysiology 2005 ;16(8):823-829

Ablation of idiopathic right ventricular outflow tract tachycardia: current perspectivesJoshi,S.; Wilber,D. J.Journal of cardiovascular electrophysiology 2005 ;16(Suppl 1):S52-8

Influence of age and gender on the mechanism of supraventricular tachycardiaPorter,M. J.; Morton,J. B.; Denman,R.; Lin,A. C.; Tierney,S.; Santucci,P. A.; Cai,J. J.; Madsen,N.; Wilber,D. J.Heart Rhythm 2004 ;1(4):393-396

Electroanatomic mapping of the right ventricle in a patient with a giant epsilon wave, ventricular tachycardia, and cardiac sarcoidosis.Santucci,P. A.; Morton,J. B.; Picken,M. M.; Wilber,D. J.Journal of cardiovascular electrophysiology 2004 ;15(9):1091-1094

Medical School
  • Northwestern University Feinberg School of Medicine
  • Northwestern University McGaw Medical Center, Internal Medicine: General
  • Massachusetts General Hospital, Clinical Cardiac Electrophysiology
  • University of Michigan Medical Center, Cardiology
  • French
  • Bicycling