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February 22, 2012
Celiac Disease is Linked to Osteoporosis
One family finds autoimmune disease can lead to bone disorder later in life
MAYWOOD, Ill. -- People with celiac disease are at risk for osteoporosis, according to physicians at Loyola University Health System (LUHS). A 2009 New England Journal of Medicine study supports this correlation. Researchers believe that people with celiac disease may develop osteoporosis because their body poorly absorbs calcium and vitamin D, which are necessary for bone health.
Celiac disease is an inherited autoimmune disorder that damages the small intestine and does not allow nutrients to properly absorb when foods containing gluten are ingested. Gluten is found in grains such as wheat, rye, barley and triticale. Patients with celiac disease must eliminate foods containing this protein or risk further damage.
“Many people with celiac disease go on to develop osteoporosis later in life,” said Pauline Camacho, MD, director of the LUHS Osteoporosis and Metabolic Bone Disease Center. “We attribute this to the fact that patients with celiac disease do not get the proper amount of nutrients necessary for bone function, which leads to rapid bone destruction and severe osteoporosis."
For the Bobel family, this certainly is the trend. The family first learned that they were at risk for this debilitating disease when Rebecca Bobel, 71, fractured her pelvis, hip and tailbone at age 50. She was diagnosed with osteoporosis at the time and doctors later learned that she carries the gene for celiac disease. Bobel also went on to develop hypothyroidism, another autoimmune disorder, and vitamin D deficiency, which is common in people with these disorders. Today, she is being treated for each of these conditions at Loyola.
“People with one autoimmune disorder are at risk for developing other autoimmune disorders,” Dr. Camacho said. “This was extremely apparent with the Bobel family where we saw more than one disorder in each family member we treated."
Bobel’s daughter Kim Lewis, 47, learned that she had celiac disease and vitamin D deficiency after she stopped absorbing her medication for hypothyroidism. She has since switched to a gluten-free diet and has started taking calcium, magnesium and vitamin D supplements. These lifestyle changes have allowed her to ward off osteoporosis. However, Lewis continues to get screened yearly for the disease and quarterly for her other autoimmune disorders.
“It is critical to get checked for celiac disease at an early age if you have a family history of this disorder and osteoporosis,” Lewis said. “Doctors caught my various autoimmune disorders early and have been able to prevent osteoporosis from developing as a result. Now I have to educate my daughters and nieces about these conditions to help them protect their health."
Lewis’ niece Nicole Gaynor, 31, was diagnosed with celiac disease in the last year after she experienced prolonged symptoms of bloating. Dr. Camacho was concerned that she wasn’t properly absorbing the nutrients in her food, so she worked with a team of Loyola gastrointestinal specialists and confirmed that Gaynor had the disease. Gaynor has since made rigorous diet changes that have stopped her celiac disease from progressing. She also has been treated successfully for hypothyroidism and vitamin D deficiency.
“While altering my diet has been challenging, it is much easier than coping with the broken bones that come with osteoporosis,” Gaynor said. “I have seen my grandma suffer from the painful side effects of osteoporosis, and I want to prevent that from happening to my other family members and me."
To view a video of this family, visit: http://www.youtube.com/watch?v=dCIiMIXXxZU
Loyola University Health System (LUHS) is a member of Trinity Health. Based in the western suburbs of Chicago, LUHS is a quaternary care system with a 61-acre main medical center campus, the 36-acre Gottlieb Memorial Hospital campus and more than 30 primary and specialty care facilities in Cook, Will and DuPage counties. The medical center campus is conveniently located in Maywood, 13 miles west of the Chicago Loop and 8 miles east of Oak Brook, Ill. The heart of the medical center campus is a 559-licensed-bed hospital that houses a Level 1 Trauma Center, a Burn Center and the Ronald McDonald® Children's Hospital of Loyola University Medical Center. Also on campus are the Cardinal Bernardin Cancer Center, Loyola Outpatient Center, Center for Heart & Vascular Medicine and Loyola Oral Health Center as well as the LUC Stritch School of Medicine, the LUC Marcella Niehoff School of Nursing and the Loyola Center for Fitness. Loyola's Gottlieb campus in Melrose Park includes the 255-licensed-bed community hospital, the Professional Office Building housing 150 private practice clinics, the Adult Day Care, the Gottlieb Center for Fitness, Loyola Center for Metabolic Surgery and Bariatric Care and the Loyola Cancer Care & Research at the Marjorie G. Weinberg Cancer Center at Melrose Park.