Neurosciences Clinical Research

This is a listing of Loyola University Health System Neurosciences clinical research that is open and actively recruiting patients. Please click on the name of the research for a brief description, eligibility requirements and contact information. All research listed below have been approved by Loyola's Institutional Review Board chairman for promotion on our Web site.

For more information call (888) LUHS-888.

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PSOLAR Registry Study for Psoriasis

The registry study will track the behavior of the disease in response to other therapies, such as adalimumab, alefacept, certolizumab pegol, efalizumab, etanercept and other biologics. The registry also will evaluate clinical outcomes, quality of life and potential risks for participants who may receive standard therapies for psoriasis.

Cardiovascular Health: Atherosclerosis

TIMI-50 Atherosclerosis Study

The purpose is to evaluate patients with blockages in one or more arteries supplying blood to the heart, brain or legs. The study will evaluate if the study drug blocks platelet build-up which can cause blockage.

Mental Health: Depression

Quetiapine May Lower Cardiovascular Risk Due to Depression and Anxiety

The purpose of this study is to determine if quetiapine can reverse the arterial stiffening that often occurs in depression and anxiety, which are believed to be risk factors for future heart disease.

Arterial stiffness will be measured non-invasively by a procedure called applanation tonometry. The measures serve as markers of subclinical hardening of the arteries and may be able to show a response to therapy, if such hardening is present. The procedure involves positioning of a probe on the skin overlaying certain arteries in the body, namely the radial, carotid and femoral. Heart rate variability similarly is determined non-invasively by placing three leads on the chest and determining heart function. Treatment with quetiapine may restore normal heart function.

Stroke

IRIS: Insulin Resistance Intervention After Stroke Trial

Both stroke and heart attack are serious medical problems. The purpose of this study is to see if stroke and heart attack can be reduced in insulin resistant non-diabetic adults using an approved drug versus a placebo (inactive drug).

The Experience of Female Caregivers of Stroke Survivors

The purpose of this study is to describe how female caregivers of stroke survivors cope with the stress of care-giving.