Clinical Research Details
Title:
Phase II Study to Evaluate Efficacy and Safety of Adjuvant High-Dose Rate Brachytherapy (delivered using the mammosite applicator) as the Sole Method of Radiation Therapy for Selected Women with Stage I Breast Cancer-Small Volume DCIS
Purpose:
The study seeks to test whether radiation to part of the breast using brachytherapy after the removal of cancer gives similar results to those obtained when the whole breast receives RT. The study also seeks to assess safety of the mammosite device in this setting, including the quality of life.
Study Number:
14179121802
Number of Patients:
50
Elgibility:
Eligible patients will be older than 50 years of age, stage T1 (lesions <2cm), N0M0, negative surgical lesions (>2mm), histological grade I-III, no extensive intraductal component, unifocal breat cancer, unilateral breast cancer, no diffuse lymphovascular invatsion, and ER positive or negative.
Treatment:
Patients will receive radiation therapy to the lumpectomy cavity using the mammosite catheter. Treatment is given twice a day (six hours apart) for five working days.
Principal Investigator:
Enrollment Phone:
(708) 216-2568