Clinical Research Details
Title:
RTOG 0413 NSABP B-39 A Randomized Phase III Study of Conventional Whole Breast Radiation vs. Partial Breast Radiation for Women with Stage 0, I or II Breast Cancer
Purpose:
The purpose of this study is to determine whether partial breast irradiation (PBI) limited to the region of the tumor bed following lumpectomy provides equivalent local tumor control in the breast compared to conventional whole breast irradiation (WBI) in the local management of early stage breast cancer.
Study Number:
LU 108204
Number of Patients:
4300
Elgibility:
Patients must be 18 years or older. The patient must have stage 0, I or II breast cancer. If stage II, the tumor size must be 3 cm or less. The tumor must be ductal carinoma insitu or invasive adenocarcinoma of the breast. Surgical treatment of the breast must have been a lumpectomy. Patients with invasive breast cancer are required to have axillary staging.
Treatment:
Patients are randomly assigned to receive either whole breast radiation or partial breast radiation. Patients who receivewhole breast radiation will receive radiation once a day for five days a week. Whole breast radiation will last five to seven weeks. Each treatment lasts 10 to 15 minutes. Patients who receive partial breast radiation will receive radiation two times a day, about six hours apart for five days. Each treatment lasts for 10 to 15 minutes.
Principal Investigator:
Enrollment Phone:
(708) 216-2568